Blood-Brain Barrier (BBB) disruption is an important pathophysiological process of acute
ischemic stroke (AIS), resulting in devastating malignant brain edema and hemorrhagic …

Stroke is one of the leading causes of death and long-term disability worldwide. More than
80% of strokes are ischemic, caused by an occlusion of cerebral arteries. Without question …

Ischemic stroke (IS) is one of the most common causes of disability and death. Thrombolysis
and neuroprotection are two current major therapeutic strategies to overcome ischemic and …

Intracerebral hemorrhage associated with thrombolytic therapy with tissue plasminogen
activator (tPA) in acute ischemic stroke continues to present a major clinical problem. Here …

Brain inflammation is regarded as one of the leading causes that aggravates secondary
brain injury and hinders the prognosis of ischemic stroke. After ischemic stroke, high …

Increasing evidences suggest that inflammation plays a key role in the pathogenesis of
stroke, a devastating disease second only to cardiac ischemia as a cause of death …

Intracerebral hemorrhage following blood–brain barrier (BBB) disruption resulting from
thrombolysis of ischemic stroke with tissue plasminogen activator (tPA) remains a critical …

Stroke is a threatening cerebrovascular disease caused by thrombus with high morbidity
and mortality rates. Neutrophils are the first to be recruited in the brain after stroke, which …

Thrombolysis with tissue plasminogen activator (tPA) provides the most common therapy for
ischemic stroke onset within the past 4.5 h. However, enhanced neutrophil infiltration and …

Background and purpose To explore the association of systemic inflammatory index (SIRI),
systemic immune-inflammatory index (SII) and inflammatory prognosis index (IPI) with 90d …