The development and progression of diabetic kidney disease (DKD), a highly prevalent
complication of diabetes mellitus, are influenced by both genetic and environmental factors …

Precise gene editing is—or will soon be—in clinical use for several diseases, and more
applications are under development. The programmable nuclease Cas9, directed by a …

Globally, more than 5 million people die annually from lack of access to critical treatments for
kidney disease—by 2040, chronic kidney disease is projected to be the fifth leading cause of …

The CRISPR-Cas9 technology has changed the landscape of genome editing and has
demonstrated extraordinary potential for treating otherwise incurable diseases. Engineering …

In 2016, second‐generation genetically modified (GM) potatoes were approved for
production and sale in Canada. In this study, we analyze how consumer acceptance of GM …

Alport syndrome (AS) is a hereditary kidney disease associated with proteinuria, hematuria
and progressive kidney failure. It is characterized by a defective glomerular basement …

Painted turtles are remarkable for their freeze tolerance and supercooling ability along with
their associated resilience to hypoxia/anoxia and oxidative stress, rendering them an ideal …

The kidney tubules provide homeostasis by maintaining the external milieu that is critical for
proper cellular function. Without homeostasis, there would be no heartbeat, no muscle …

The clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR‐
related protein 9 (Cas9) genome editing system has attracted much attention due to its …

Genome editing technologies, clustered regularly interspaced short palindromic repeats
(CRISPR)-Cas in particular, have revolutionized the field of genetic engineering, providing …