Metabolic burden is defined by the influence of genetic manipulation and environmental
perturbations on the distribution of cellular resources. The rewiring of microbial metabolism …

Microbial fermentations are used for the sustainable production of a range of products. Due
to increasing trends in the food sector toward plant-based foods and meat and dairy product …

Plastic debris in the global biosphere is an increasing concern, and nanoplastic (NPs)
toxicity in humans is far from being understood. Studies have indicated that NPs can affect …

Enzyme turnover numbers (k cat) are key to understanding cellular metabolism, proteome
allocation and physiological diversity, but experimentally measured k cat data are sparse …

Energy metabolism (encompassing energy assimilation, conversion and utilization) plays a
central role in all life processes and serves as a link between the organismal physiology …

Genome-scale metabolic models (GEMs) are computational representations that enable
mathematical exploration of metabolic behaviors within cellular and environmental …

Metabolic efficiency profoundly influences organismal fitness. Nonphotosynthetic organisms,
from yeast to mammals, derive usable energy primarily through glycolysis and respiration …

Genome-scale metabolic models (GEMs) have been widely used for quantitative exploration
of the relation between genotype and phenotype. Streamlined integration of enzyme …

When conditions change, unicellular organisms rewire their metabolism to sustain cell
maintenance and cellular growth. Such rewiring may be understood as resource re …

Aerobic fermentation, also referred to as the Crabtree effect in yeast, is a well-studied
phenomenon that allows many eukaryal cells to attain higher growth rates at high glucose …