Targeted therapy for hepatocellular carcinoma

A Huang, XR Yang, WY Chung, AR Dennison… - Signal transduction and …, 2020‏ - nature.com
The last 3 years have seen the emergence of promising targeted therapies for the treatment
of hepatocellular carcinoma (HCC). Sorafenib has been the mainstay of treatment for a …

Risk factors and prevention of hepatocellular carcinoma in the era of precision medicine

N Fujiwara, SL Friedman, N Goossens, Y Hoshida - Journal of hepatology, 2018‏ - Elsevier
Patients who develop chronic fibrotic liver disease, caused by viral or metabolic aetiologies,
are at a high risk of develo** hepatocellular carcinoma (HCC). Even after complete HCC …

Systemic therapy for advanced hepatocellular carcinoma: ASCO guideline

JD Gordan, EB Kennedy, GK Abou-Alfa… - Journal of Clinical …, 2020‏ - ascopubs.org
PURPOSE To develop an evidence-based clinical practice guideline to assist in clinical
decision making for patients with advanced hepatocellular carcinoma (HCC). METHODS …

Systemic therapy for advanced hepatocellular carcinoma: ASCO guideline update

JD Gordan, EB Kennedy, GK Abou-Alfa… - Journal of Clinical …, 2024‏ - ascopubs.org
PURPOSE To update an evidence-based guideline to assist in clinical decision-making for
patients with advanced hepatocellular carcinoma (HCC). METHODS ASCO convened an …

Tumor-associated macrophages in hepatocellular carcinoma pathogenesis, prognosis and therapy

K Arvanitakis, T Koletsa, I Mitroulis, G Germanidis - Cancers, 2022‏ - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) constitutes a major health burden,
accounting for> 80% of primary liver cancers globally. Inflammation has come into the …

[HTML][HTML] Epigenetic associations between lncRNA/circRNA and miRNA in hepatocellular carcinoma

TS Han, K Hur, HS Cho, HS Ban - Cancers, 2020‏ - mdpi.com
Simple Summary Non-coding RNAs such as microRNAs, long non-coding RNAs, and
circular RNAs contribute to the development and progression of hepatocellular carcinoma …

Identification of a ferroptosis-related signature model including mRNAs and lncRNAs for predicting prognosis and immune activity in hepatocellular carcinoma

ZA Chen, H Tian, DM Yao, Y Zhang, ZJ Feng… - Frontiers in …, 2021‏ - frontiersin.org
Background Ferroptosis is a novel form of regulated cell death involved in tumor
progression. The role of ferroptosis-related lncRNAs in hepatocellular carcinoma (HCC) …

New therapeutic interventions for advanced hepatocellular carcinoma

S Bangaru, JA Marrero… - Alimentary pharmacology & …, 2020‏ - Wiley Online Library
Background Advanced hepatocellular carcinoma (HCC) portends a poor prognosis;
however recent advances in first‐line and second‐line treatment options should yield …

Cost-effectiveness of atezolizumab plus bevacizumab vs sorafenib for patients with unresectable or metastatic hepatocellular carcinoma

X Zhang, J Wang, J Shi, X Jia, S Dang… - JAMA Network …, 2021‏ - jamanetwork.com
Importance Atezolizumab plus bevacizumab as a first-line therapy for patients with
unresectable or metastatic hepatocellular carcinoma has been shown to improve overall …

Atezolizumab and bevacizumab combination compared with sorafenib as the first‐line systemic treatment for patients with unresectable hepatocellular carcinoma: a …

F Wen, H Zheng, P Zhang, W Liao, K Zhou… - Liver …, 2021‏ - Wiley Online Library
Abstract Background & Aims In patients with unresectable hepatocellular carcinoma (HCC),
the combination of atezolizumab and bevacizumab improved progression‐free survival …