The burden of premature mortality of epilepsy in high‐income countries: a systematic review from the Mortality Task Force of the International League Against Epilepsy

DJ Thurman, G Logroscino, E Beghi, WA Hauser… - …, 2017 - Wiley Online Library
Since previous reviews of epidemiologic studies of premature mortality among people with
epilepsy were completed several years ago, a large body of new evidence about this subject …

The burden of epilepsy and unmet need in people with focal seizures

P Ioannou, DL Foster, JW Sander, S Dupont… - Brain and …, 2022 - Wiley Online Library
Background Epilepsy is one of the most common neurological conditions worldwide. As a
chronic condition, epilepsy imposes a significant burden on people with epilepsy and …

Premature mortality in epilepsy and the role of psychiatric comorbidity: a total population study

S Fazel, A Wolf, N Långström, CR Newton… - The Lancet, 2013 - thelancet.com
Background Epilepsy is associated with high rates of premature mortality, but the
contribution of psychiatric comorbidity is uncertain. We assessed the prevalence and risks of …

Prevalence of active convulsive epilepsy in sub-Saharan Africa and associated risk factors: cross-sectional and case-control studies

AK Ngugi, C Bottomley, I Kleinschmidt… - The Lancet …, 2013 - thelancet.com
Background The prevalence of epilepsy in sub-Saharan Africa seems to be higher than in
other parts of the world, but estimates vary substantially for unknown reasons. We assessed …

Nonadherence to antiepileptic drugs and increased mortality: findings from the RANSOM Study

E Faught, MS Duh, JR Weiner, A Guerin… - Neurology, 2008 - AAN Enterprises
Objectives: The primary objective was to investigate whether nonadherence to antiepileptic
drugs (AEDs) is associated with increased mortality and the secondary objective to examine …

Intractable epilepsy: management and therapeutic alternatives

SU Schuele, HO Lüders - The Lancet Neurology, 2008 - thelancet.com
More than half of patients with newly diagnosed epilepsy achieve complete seizure control
without major side-effects. Patients who continue to have seizures after initial medical …

Serotonin neurones have anti‐convulsant effects and reduce seizure‐induced mortality

GF Buchanan, NM Murray, MA Hajek… - The Journal of …, 2014 - Wiley Online Library
Key points Sudden unexpected death in epilepsy is the leading cause of death in patients
with refractory epilepsy. Respiratory and cardiac impairment induced by a seizure have …

The serotonin axis: shared mechanisms in seizures, depression, and SUDEP

GB Richerson, GF Buchanan - Epilepsia, 2011 - Wiley Online Library
There is a growing appreciation that patients with seizures are also affected by a number of
comorbid conditions, including an increase in prevalence of depression (Kanner, 2009) …

[PDF][PDF] Prevention of drowning

P PREVENTION - Pediatrics, 2019 - meowmeowfoundation.org
BACKGROUND Drowning is the leading cause of injury death in US children 1 to 4 years of
age and the third leading cause of unintentional injury death among US children and …

The impact of epilepsy on patients' lives

MP Kerr - Acta Neurologica Scandinavica, 2012 - Wiley Online Library
The impact of epilepsy is multifaceted and extensive on its effects. The occurrence of
seizures is unpredictable and often dangerous, increasing the risk of injury, hospitalization …