In heart failure, alterations of Na+ and Ca2+ handling, energetic deficit, and oxidative stress
in cardiac myocytes are important pathophysiological hallmarks. Mitochondria are central to …

Sudden cardiac death (SCD) is an unexpected sudden death due to a heart condition, that
occurs within one hour of symptoms onset. SCD is a leading cause of death in western …

Cardiac arrhythmias and the resulting sudden cardiac death are significant cardiovascular
complications that continue to impose a heavy burden on patients and society. An emerging …

Telomere length measurement is increasingly recognized as a clinical gauge for age-related
disease risk. There are several methods for studying blood telomere length (BTL) as a …

Influx of sodium ions through voltage-gated sodium channels in cardiomyocytes is essential
for proper electrical conduction within the heart. Both acquired conditions associated with …

There is increasing evidence regarding the prevalence of genetic cardiomyopathies, for
which arrhythmias may be the first presentation. Ventricular and atrial arrhythmias …

Ventricular arrhythmia and subsequent sudden cardiac death (SCD) due to acute
myocardial infarction (AMI) is one of the most frequent causes of death in humans. Lethal …

Heart failure is a serious global health challenge, affecting more than 6.2 million people in
the United States and is projected to reach over 8 million by 2030. Independent of etiology …

OBJECTIVE Recent studies have suggested that nonalcoholic fatty liver disease (NAFLD) is
associated with an increased risk of heart rate–corrected QT interval prolongation and atrial …

Cardiac arrhythmias can follow disruption of the normal cellular electrophysiological
processes underlying excitable activity and their tissue propagation as coherent wavefronts …