Ethnopharmacological relevance Diabetes mellitus remains the most lethal metabolic
disease of contemporaneous times and despite the therapeutic arsenal currently available …

Abstract Type 2 diabetes (T2D) is a chronic metabolic disease with a high impact on public
health and social welfare. Hyperglycemia is a characteristic of T2D that leads to different …

Betulinic acid (BA), an important pentacyclic triterpene widely distributed in many foods,
possesses high antidiabetic activity. In this study, BA was found to exhibit stronger inhibition …

The postprandial hyperglycemia of diabetic patients is associated with a-amylase and a-
glucosidase, searching safer enzyme inhibitors and deciphering their inhibition mechanism …

This study was designed to investigate quantitatively the inhibition and molecular
mechanism of pancreatic α-amylase exhibited by flavonoids from dandelion to reveal its …

Alternanthera bettzickiana is being used as a folk remedy for treating arthritis by
conventional healers in Thailand. The current research was undertaken to explore the …

Psidium guajava fruit is a subtropical fruit, functional food and traditional medicine for the
adjuvant treatment of diabetes mellitus in China. To investigate the active components …

Leaves of Cyclocarya paliurus (CP) have a potential antihyperglycemic effect, but its active
compositions responsible for the beneficial properties remain unclear. The CP extract …

Fatty acid transport protein 2 (FATP2) is a multifunctional protein whose specific function is
determined by the type of located cell, its intracellular location, or organelle-specific …

α-Amylase inhibitors (aAIs) have been applied for the efficient management of type 2
diabetes. The aim of this study was to search for potential aAIs produced by microbial …