Closed‐loop adaptive deep brain stimulation (aDBS) can deliver individualized therapy at
an unprecedented temporal precision for neurological disorders. This has the potential to …

Two decades of cross-species neuroscience research on rapid action-stop** in the
laboratory has provided motivation for an underlying prefrontal–basal ganglia circuit. Here …

Deep brain stimulation (DBS) surgery offers a unique opportunity to record local field
potentials (LFPs), the electrophysiological population activity of neurons surrounding the …

Deep brain stimulation (DBS) treatment has proven effective in suppressing symptoms of
rigidity, bradykinesia, and tremor in Parkinson's disease. Still, patients may suffer from …

This review is part of the series on the clinical neurophysiology of movement disorders. It
focuses on Parkinson's disease and parkinsonism. The topics covered include the …

Disruption of subthalamic nucleus dynamics in Parkinson's disease leads to impairments
during walking. Here, we aimed to uncover the principles through which the subthalamic …

The last decades of research have gradually elucidated the complex functions of the
dopamine system in the vertebrate brain. The multiple roles of dopamine in motor function …

The neuromuscular circuit mechanisms of freezing of gait in Parkinson's disease have
received little study. Technological progress enables researchers chronically to sense local …

Abstract Introduction Freezing of gait (FoG) is a debilitating symptom of advanced
Parkinson's disease (PD) characterized by a sudden, episodic step** arrest despite the …

Postural instability is a detrimental and often treatment-refractory symptom of Parkinson's
disease. While many existing studies quantify the biomechanical deficits among various …