MALDI-TOF mass spectrometry as a diagnostic tool in human and veterinary helminthology: a systematic review

M Feucherolles, S Poppert, J Utzinger, SL Becker - Parasites & vectors, 2019 - Springer
Background Matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF) mass
spectrometry (MS) has become a widely used technique for the rapid and accurate …

A comprehensive, model-based review of vaccine and repeat infection trials for filariasis

CP Morris, H Evans, SE Larsen… - Clinical microbiology …, 2013 - journals.asm.org
Filarial worms cause highly morbid diseases such as elephantiasis and river blindness.
Since the 1940s, researchers have conducted vaccine trials in 27 different animal models of …

Multivalent fusion protein vaccine for lymphatic filariasis

G Dakshinamoorthy, AK Samykutty, G Munirathinam… - Vaccine, 2013 - Elsevier
Lymphatic filariasis affects approximately 3% of the whole world population. Mass drug
administration is currently the major control strategy to eradicate this infection from endemic …

Evaluation of immunomodulatory potential of recombinant histidyl-tRNA synthetase (rLdHisRS) protein of Leishmania donovani as a vaccine candidate against …

V Kushwaha, N Capalash - Acta Tropica, 2023 - Elsevier
Visceral leishmaniasis is neglected tropical protozoan disease caused by Leishmania
donovani and are associated with high fatality rate in develo** countries since …

[HTML][HTML] Harnessing immune evasion strategy of lymphatic filariae: A therapeutic approach against inflammatory and infective pathology

P Bhoj, N Togre, V Khatri, K Goswami - Vaccines, 2022 - mdpi.com
Human lymphatic filariae have evolved numerous immune evasion strategies to secure their
long-term survival in a host. These strategies include regulation of pattern recognition …

Large extracellular loop of tetraspanin as a potential vaccine candidate for filariasis

G Dakshinamoorthy, G Munirathinam, K Stoicescu… - PLoS …, 2013 - journals.plos.org
Lymphatic filariasis affects nearly 120 million people worldwide and mass preventive
chemotherapy is currently used as a strategy to control this infection. This has substantially …

Filariasis: Current status, treatment and recent advances in drug development

D Katiyar, LK Singh - Current medicinal chemistry, 2011 - ingentaconnect.com
Lymphatic filariasis, onchocerciasis and loiasis caused by human filarial nematodes are
diseases of tropical and subtropical countries causing considerable morbidity. The available …

Immunization with L. sigmodontis Microfilariae Reduces Peripheral Microfilaraemia after Challenge Infection by Inhibition of Filarial Embryogenesis

S Ziewer, MP Hübner, B Dubben… - PLoS neglected …, 2012 - journals.plos.org
Background Lymphatic filariasis and onchocerciasis are two chronic diseases mediated by
parasitic filarial worms causing long term disability and massive socioeconomic problems …

The helminth parasite proteome at the host–parasite interface–Informing diagnosis and control

AM van der Ree, F Mutapi - Experimental parasitology, 2015 - Elsevier
Helminth parasites are a significant health burden for humans in the develo** world and
also cause substantial economic losses in livestock production across the world. The …

Identification and characterization of nematode specific protective epitopes of Brugia malayi TRX towards development of synthetic vaccine construct for lymphatic …

J Madhumathi, PR Prince, G Anugraha, P Kiran… - Vaccine, 2010 - Elsevier
Although multi-epitope vaccines have been evaluated for various diseases, they have not
yet been investigated for lymphatic filariasis. Here, we report for the first time identification of …