Balancing risks and benefits of cannabis use: umbrella review of meta-analyses of randomised controlled trials and observational studies

M Solmi, M De Toffol, JY Kim, MJ Choi, B Stubbs… - bmj, 2023 - bmj.com
Objective To systematically assess credibility and certainty of associations between
cannabis, cannabinoids, and cannabis based medicines and human health, from …

Medicinal properties of cannabinoids, terpenes, and flavonoids in cannabis, and benefits in migraine, headache, and pain: an update on current evidence and …

EP Baron - Headache: The Journal of Head and Face Pain, 2018 - Wiley Online Library
Background Comprehensive literature reviews of historical perspectives and evidence
supporting cannabis/cannabinoids in the treatment of pain, including migraine and …

Animal to human translation: a systematic sco** review of reported concordance rates

CHC Leenaars, C Kouwenaar, FR Stafleu… - Journal of translational …, 2019 - Springer
Background Drug development is currently hampered by high attrition rates; many
developed treatments fail during clinical testing. Part of the attrition may be due to low …

An overview of cannabidiol as a multifunctional drug: pharmacokinetics and cellular effects

N Martinez Naya, J Kelly, G Corna, M Golino… - Molecules, 2024 - mdpi.com
Cannabidiol (CBD), a non-psychoactive compound derived from Cannabis Sativa, has
garnered increasing attention for its diverse therapeutic potential. This comprehensive …

[HTML][HTML] The effects of cannabidiol, a non-intoxicating compound of cannabis, on the cardiovascular system in health and disease

A Kicman, M Toczek - International journal of molecular sciences, 2020 - mdpi.com
Cannabidiol (CBD) is a non-intoxicating and generally well-tolerated constituent of cannabis
which exhibits potential beneficial properties in a wide range of diseases, including …

The therapeutic potential of purified cannabidiol

SE O'Sullivan, SS Jensen, GN Nikolajsen… - Journal of Cannabis …, 2023 - Springer
The use of cannabidiol (CBD) for therapeutic purposes is receiving considerable attention,
with speculation that CBD can be useful in a wide range of conditions. Only one product, a …

Cannabinoids as medicinals

JH Khalsa, G Bunt, K Blum, SB Maggirwar… - Current addiction …, 2022 - Springer
Purpose of review There have been many debates, discussions, and published writings
about the therapeutic value of cannabis plant and the hundreds of cannabinoids it contains …

A single dose of cannabidiol reduces blood pressure in healthy volunteers in a randomized crossover study

KA Jadoon, GD Tan, SE O'Sullivan - JCI insight, 2017 - pmc.ncbi.nlm.nih.gov
BACKGROUND. Cannabidiol (CBD) is a nonpsychoactive phytocannabinoid used in
multiple sclerosis and intractable epilepsies. Preclinical studies show CBD has numerous …

Cannabidiol and sports performance: a narrative review of relevant evidence and recommendations for future research

D McCartney, MJ Benson, B Desbrow, C Irwin… - Sports medicine …, 2020 - Springer
Cannabidiol (CBD) is a non-intoxicating cannabinoid derived from Cannabis sativa. CBD
initially drew scientific interest due to its anticonvulsant properties but increasing evidence of …

A placebo‐controlled investigation of the analgesic effects, abuse liability, safety and tolerability of a range of oral cannabidiol doses in healthy humans

CA Arout, M Haney, ES Herrmann… - British journal of …, 2022 - Wiley Online Library
Aims Preclinical studies demonstrate that cannabidiol (CBD) elicits an antinociceptive
response in animal models of neuropathic pain; in humans, limited data are available to …