Mechanical properties of extracellular matrices (ECMs) regulate essential cell behaviours,
including differentiation, migration and proliferation, through mechanotransduction. Studies …

Cells and tissues generate and are exposed to various mechanical forces that act across a
range of scales, from tissues to cells to organelles. Forces provide crucial signals to inform …

Matrigel, a basement-membrane matrix extracted from Engelbreth–Holm–Swarm mouse
sarcomas, has been used for more than four decades for a myriad of cell-culture …

Abstract 3D printing alias additive manufacturing can transform 3D virtual models created by
computer-aided design (CAD) into physical 3D objects in a layer-by-layer manner …

Transplantation of mesenchymal stem cells (MSCs) holds promise to repair severe traumatic
injuries. However, current transplantation practices limit the potential of this technique, either …

Over 90% of potential anti-cancer drug candidates results in translational failures in clinical
trials. The main reason for this failure can be attributed to the non-accurate pre-clinical …

Diabetes is associated with an altered global inflammatory state with impaired wound
healing. Mesenchymal stem/stromal cells (MSC) are being explored for treatment of diabetic …

Tissue engineering (TE) is a rapidly growing interdisciplinary field, which aims to restore or
improve lost tissue function. Despite that TE was introduced more than 20 years ago …

The musculoskeletal system plays a critical role in providing the physical scaffold and
movement to the mammalian body. Musculoskeletal disorders severely affect mobility and …

Traumatic injuries, tumor resections, and degenerative diseases can damage skeletal
muscle and lead to functional impairment and severe disability. Skeletal muscle …