Respiratory syncytial virus infection: treatments and clinical management

S Malik, T Ahmad, K Muhammad, Y Waheed - Vaccines, 2023 - mdpi.com
Respiratory syncytial virus (RSV) is a major healthcare concern, especially for immune-
compromised individuals and infants below 5 years of age. Worldwide, it is known to be …

[HTML][HTML] Vaccine potentiation by combination adjuvants

B Levast, S Awate, L Babiuk, G Mutwiri, V Gerdts… - Vaccines, 2014 - mdpi.com
Adjuvants are crucial components of vaccines. They significantly improve vaccine efficacy by
modulating, enhancing, or extending the immune response and at the same time reducing …

S1 domain of the porcine epidemic diarrhea virus spike protein as a vaccine antigen

N Makadiya, R Brownlie, J van den Hurk, N Berube… - Virology journal, 2016 - Springer
Background Porcine epidemic diarrhea virus (PEDV) is a highly contagious virus infecting
pigs of all ages with high morbidity and mortality among newborn piglets. Currently, there is …

Mucosal delivery of a double-stapled RSV peptide prevents nasopulmonary infection

GH Bird, S Boyapalle, T Wong, K Opoku-Nsiah… - The Journal of clinical …, 2014 - jci.org
Respiratory syncytial virus (RSV) infection accounts for approximately 64 million cases of
respiratory disease and 200,000 deaths worldwide each year, yet no broadly effective …

Thermoresponsive polymer nanoparticles co-deliver RSV F trimers with a TLR-7/8 adjuvant

JR Francica, GM Lynn, R Laga, MG Joyce… - Bioconjugate …, 2016 - ACS Publications
Structure-based vaccine design has been used to develop immunogens that display
conserved neutralization sites on pathogens such as HIV-1, respiratory syncytial virus …

Human In vitro Modeling Identifies Adjuvant Combinations that Unlock Antigen Cross-presentation and Promote T-helper 1 Development in Newborns, Adults and …

S Thomas, J Pak, S Doss-Gollin, K Ryff… - Journal of Molecular …, 2024 - Elsevier
Adjuvants are vaccine components that can boost the type, magnitude, breadth, and
durability of an immune response. We have previously demonstrated that certain adjuvant …

Polyphosphazenes as adjuvants for animal vaccines and other medical applications

DJ Chand, RB Magiri, HL Wilson… - … in bioengineering and …, 2021 - frontiersin.org
Polyphosphazenes are a class of experimental adjuvants that have shown great versatility
as vaccine adjuvants in many animal species ranging from laboratory rodents to large …

Nanoscale Peptide Self-assemblies Boost BCG-primed Cellular Immunity Against Mycobacterium tuberculosis

CB Chesson, M Huante, RJ Nusbaum, AG Walker… - Scientific reports, 2018 - nature.com
Abstract Bacillus Calmette-Guerin (BCG) is the only vaccine against TB and has limited
protection efficacy, which wanes past adolescence. Multifunctional CD8+ T cells (IFN …

A novel combination adjuvant platform for human and animal vaccines

R Garg, L Babiuk, V Gerdts - Vaccine, 2017 - Elsevier
Adjuvants are crucial components of many vaccines. They are used to improve the
immunogenicity of vaccines with the aim of conferring long-term protection, to enhance the …

[PDF][PDF] Adjuvants for veterinary vaccines--types and modes of action

V Gerdts - Berl Munch Tierarztl Wochenschr, 2015 - vetline.de
Adjuvants are used to improve the immune response to vaccines. Formulation with
adjuvants can result in an earlier onset of immunity, an overall stronger immune response, a …