Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums

SE Arnold, Z Arvanitakis… - Nature Reviews …, 2018 - nature.com
Considerable overlap has been identified in the risk factors, comorbidities and putative
pathophysiological mechanisms of Alzheimer disease and related dementias (ADRDs) and …

Role of gut microbiota and nutrients in amyloid formation and pathogenesis of Alzheimer disease

F Pistollato, S Sumalla Cano, I Elio… - Nutrition …, 2016 - academic.oup.com
It has been hypothesized that alterations in the composition of the gut microbiota might be
associated with the onset of certain human pathologies, such as Alzheimer disease, a …

Modifiable predictors of dementia in mild cognitive impairment: a systematic review and meta-analysis

C Cooper, A Sommerlad, CG Lyketsos… - American Journal of …, 2015 - Am Psychiatric Assoc
Objective: Public health campaigns encouraging early help seeking have increased rates of
mild cognitive impairment (MCI) diagnosis in Western countries, but we know little about …

Type 2 diabetes mellitus and Alzheimer's disease: shared molecular mechanisms and potential common therapeutic targets

R Hamzé, E Delangre, S Tolu, M Moreau… - International journal of …, 2022 - mdpi.com
The global prevalence of diabetes mellitus and Alzheimer's disease is increasing alarmingly
with the aging of the population. Numerous epidemiological data suggest that there is a …

Mild cognitive impairment and progression to dementia in people with diabetes, prediabetes and metabolic syndrome: a systematic review and meta-analysis

K Pal, N Mukadam, I Petersen, C Cooper - Social psychiatry and …, 2018 - Springer
Purpose We aimed to quantify the relative risk of progression from mild cognitive impairment
(MCI) to dementia in people with and without diabetes, and with and without the MetS …

The interplay among oxidative stress, brain insulin resistance and AMPK dysfunction contribute to neurodegeneration in type 2 diabetes and Alzheimer disease

E Barone, F Di Domenico, M Perluigi… - Free Radical Biology and …, 2021 - Elsevier
Alzheimer's disease (AD) is the most common form of dementia in the elderly followed by
vascular dementia. In addition to clinically diagnosed dementia, cognitive dysfunction has …

Diet in the prevention of Alzheimer's disease: current knowledge and future research requirements

O Stefaniak, M Dobrzyńska, S Drzymała-Czyż… - Nutrients, 2022 - mdpi.com
Alzheimer's disease is a progressive brain disease that is becoming a major health problem
in today's world due to the aging population. Despite it being widely known that diet has a …

[HTML][HTML] Elevated risk of type 2 diabetes for development of Alzheimer disease: a key role for oxidative stress in brain

DA Butterfield, F Di Domenico, E Barone - Biochimica et Biophysica Acta …, 2014 - Elsevier
Alzheimer disease (AD) is the most common form of dementia among the elderly and is
characterized by progressive loss of memory and cognition. Epidemiological data show that …

Recent publications from the Alzheimer's Disease Neuroimaging Initiative: Reviewing progress toward improved AD clinical trials

MW Weiner, DP Veitch, PS Aisen, LA Beckett… - Alzheimer's & …, 2017 - Elsevier
Abstract Introduction The Alzheimer's Disease Neuroimaging Initiative (ADNI) has continued
development and standardization of methodologies for biomarkers and has provided an …

Nutritional patterns associated with the maintenance of neurocognitive functions and the risk of dementia and Alzheimer's disease: A focus on human studies

F Pistollato, RC Iglesias, R Ruiz, S Aparicio… - Pharmacological …, 2018 - Elsevier
Ample epidemiological evidence suggests a strong correlation among diet, lifestyle factors
and the onset and consolidation of dementia and Alzheimer's disease (AD). It has been …