Whole blood, as one of the most significant biological fluids, provides critical information for
health management and disease monitoring. Over the past 10 years, advances in …

Aptamers are short oligonucleotides isolated in vitro from randomized libraries that can bind
to specific molecules with high affinity, and offer a number of advantages relative to …

Nature achieves differentiation of specific and nonspecific binding in molecular interactions
through precise control of biomolecules in space and time. Artificial systems such as …

Biosensors are utilized in several different fields, including medicine, food, and the
environment; in this review, we examine recent developments in biosensors for healthcare …

Beyond traditional needs of biosensors such as high sensitivity and selectivity for analyte
detection, newly emerging requirements including a real-time detection ability and in-field …

The continuous, real-time measurement of specific molecules in situ in the body would
greatly improve our ability to understand, diagnose, and treat disease. The vast majority of …

Rapid progress in identifying biomarkers that are hallmarks of disease has increased
demand for high-performance detection technologies. Implementation of electrochemical …

The combination of nanostructures with biomolecules leading to the generation of functional
nanosystems holds great promise for biotechnological and biomedical applications. As a …

The development of a technology capable of tracking the levels of drugs, metabolites, and
biomarkers in the body continuously and in real time would advance our understanding of …

We performed in vitro selection experiments to identify DNA aptamers for the S1 subunit of
the SARS-CoV-2 spike protein (S1 protein). Using a pool of pre-structured random DNA …