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BCS class IV drugs: Highly notorious candidates for formulation development
BCS class IV drugs (eg, amphotericin B, furosemide, acetazolamide, ritonavir, paclitaxel)
exhibit many characteristics that are problematic for effective oral and per oral delivery …
exhibit many characteristics that are problematic for effective oral and per oral delivery …
Spring and parachute: How cocrystals enhance solubility
DD Bavishi, CH Borkhataria - … in Crystal Growth and Characterization of …, 2016 - Elsevier
This article is intended to combine literature on cocrystallization–a tool for enhancing the
solubility and for improving the physicochemical properties of an API (an API is the molecule …
solubility and for improving the physicochemical properties of an API (an API is the molecule …
Pharmaceutical co-crystallization: Regulatory aspects, design, characterization, and applications
AR Thayyil, T Juturu, S Nayak… - Advanced …, 2020 - pmc.ncbi.nlm.nih.gov
Pharmaceutical co-crystals are novel class of pharmaceutical substances, which possess an
apparent probability of advancement of polished physical properties offering stable and …
apparent probability of advancement of polished physical properties offering stable and …
Pharmaceutical co‐crystal: An alternative strategy for enhanced physicochemical properties and drug synergy
JB Ngilirabanga, H Samsodien - Nano Select, 2021 - Wiley Online Library
A growing number of co‐crystals in the literature are proof of how significant the co‐
crystallization concept has become. Co‐crystallization enhances physicochemical …
crystallization concept has become. Co‐crystallization enhances physicochemical …
Mechanochemical approaches to pharmaceutical cocrystal formation and stability analysis
SY Lin - Current pharmaceutical design, 2016 - ingentaconnect.com
Solid-state mechanochemical grinding is important for promoting cocrystal formation,
particularly in the design of new solids in the pharmaceutical industry. Pharmaceutical …
particularly in the design of new solids in the pharmaceutical industry. Pharmaceutical …
Synthon hierarchy in theobromine cocrystals with hydroxybenzoic acids as coformers
Pharmaceutical cocrystals, multicomponent solids composed of molecular and/or ionic
compounds connected by noncovalent interactions, are objects of interest in crystal …
compounds connected by noncovalent interactions, are objects of interest in crystal …
Microwave coprocessing of modafinil with Gelucire®: Thermal and compression characteristics: Original scientific article
D Omari, A Sallam, I Rashid, SM Assaf… - ADMET and …, 2025 - pub.iapchem.org
Introduction: Modafinil, a wakefulness-promoting agent, is primarily used to treat excessive
daytime sleepiness associated with narcolepsy and fatigue. As a BCS class II drug …
daytime sleepiness associated with narcolepsy and fatigue. As a BCS class II drug …
[PDF][PDF] Effect of seed loading and temperature of seeding on carbamazepine-saccharin co-crystal
Objectives: In pharmaceutical industries, the properties of desired final crystal can be
modified by seeding process. Seeding activities depend on seed loading, seed size, seed …
modified by seeding process. Seeding activities depend on seed loading, seed size, seed …
[PDF][PDF] Synthesis, Characterization and Performance Evaluation of Aceclofenac-Urea Cocrystals.
Aceclofenac is one of the commonly used Nonsteroidal anti-inflammatory drugs
representing the variety of therapeutic applications including management of pain …
representing the variety of therapeutic applications including management of pain …
Salts of purine alkaloids caffeine and theobromine with 2, 6-dihydroxybenzoic acid as coformer: structural, theoretical, thermal and spectroscopic studies
The study of various forms of pharmaceutical substances with specific physicochemical
properties suitable for putting them on the market is one of the elements of research in the …
properties suitable for putting them on the market is one of the elements of research in the …