BCS class IV drugs: Highly notorious candidates for formulation development

R Ghadi, N Dand - Journal of Controlled Release, 2017 - Elsevier
BCS class IV drugs (eg, amphotericin B, furosemide, acetazolamide, ritonavir, paclitaxel)
exhibit many characteristics that are problematic for effective oral and per oral delivery …

Spring and parachute: How cocrystals enhance solubility

DD Bavishi, CH Borkhataria - … in Crystal Growth and Characterization of …, 2016 - Elsevier
This article is intended to combine literature on cocrystallization–a tool for enhancing the
solubility and for improving the physicochemical properties of an API (an API is the molecule …

Pharmaceutical co-crystallization: Regulatory aspects, design, characterization, and applications

AR Thayyil, T Juturu, S Nayak… - Advanced …, 2020 - pmc.ncbi.nlm.nih.gov
Pharmaceutical co-crystals are novel class of pharmaceutical substances, which possess an
apparent probability of advancement of polished physical properties offering stable and …

Pharmaceutical co‐crystal: An alternative strategy for enhanced physicochemical properties and drug synergy

JB Ngilirabanga, H Samsodien - Nano Select, 2021 - Wiley Online Library
A growing number of co‐crystals in the literature are proof of how significant the co‐
crystallization concept has become. Co‐crystallization enhances physicochemical …

Mechanochemical approaches to pharmaceutical cocrystal formation and stability analysis

SY Lin - Current pharmaceutical design, 2016 - ingentaconnect.com
Solid-state mechanochemical grinding is important for promoting cocrystal formation,
particularly in the design of new solids in the pharmaceutical industry. Pharmaceutical …

Synthon hierarchy in theobromine cocrystals with hydroxybenzoic acids as coformers

M Gołdyn, D Larowska, W Nowak… - …, 2019 - pubs.rsc.org
Pharmaceutical cocrystals, multicomponent solids composed of molecular and/or ionic
compounds connected by noncovalent interactions, are objects of interest in crystal …

Microwave coprocessing of modafinil with Gelucire®: Thermal and compression characteristics: Original scientific article

D Omari, A Sallam, I Rashid, SM Assaf… - ADMET and …, 2025 - pub.iapchem.org
Introduction: Modafinil, a wakefulness-promoting agent, is primarily used to treat excessive
daytime sleepiness associated with narcolepsy and fatigue. As a BCS class II drug …

[PDF][PDF] Effect of seed loading and temperature of seeding on carbamazepine-saccharin co-crystal

KA Mohammad, SA Rahim… - Indian Journal of Science …, 2017 - academia.edu
Objectives: In pharmaceutical industries, the properties of desired final crystal can be
modified by seeding process. Seeding activities depend on seed loading, seed size, seed …

[PDF][PDF] Synthesis, Characterization and Performance Evaluation of Aceclofenac-Urea Cocrystals.

S Kumar, A Gupta, CK Mishra… - Indian Journal of …, 2020 - pdfs.semanticscholar.org
Aceclofenac is one of the commonly used Nonsteroidal anti-inflammatory drugs
representing the variety of therapeutic applications including management of pain …

Salts of purine alkaloids caffeine and theobromine with 2, 6-dihydroxybenzoic acid as coformer: structural, theoretical, thermal and spectroscopic studies

M Gołdyn, A Komasa, M Pawlaczyk… - Crystal Structure …, 2021 - journals.iucr.org
The study of various forms of pharmaceutical substances with specific physicochemical
properties suitable for putting them on the market is one of the elements of research in the …