Imaging biomarkers of vulnerable carotid plaques for stroke risk prediction and their potential clinical implications

L Saba, T Saam, HR Jäger, C Yuan… - The Lancet …, 2019 - thelancet.com
Stroke represents a massive public health problem. Carotid atherosclerosis plays a
fundamental part in the occurence of ischaemic stroke. European and US guidelines for …

[HTML][HTML] Vessel wall imaging of the intracranial and cervical carotid arteries

YJ Choi, SC Jung, DH Lee - Journal of stroke, 2015 - ncbi.nlm.nih.gov
Vessel wall imaging can depict the morphologies of atherosclerotic plaques, arterial walls,
and surrounding structures in the intracranial and cervical carotid arteries beyond the simple …

The ATHEROMA (Atorvastatin Therapy: Effects on Reduction of Macrophage Activity) Study: evaluation using ultrasmall superparamagnetic iron oxide-enhanced …

TY Tang, SPS Howarth, SR Miller, MJ Graves… - Journal of the American …, 2009 - jacc.org
Objectives: The aim of this study was to evaluate the effects of low-dose (10 mg) and high-
dose (80 mg) atorvastatin on carotid plaque inflammation as determined by ultrasmall …

In vivo high-resolution MR imaging of symptomatic and asymptomatic middle cerebral artery atherosclerotic stenosis

WH Xu, ML Li, S Gao, J Ni, LX Zhou, M Yao, B Peng… - Atherosclerosis, 2010 - Elsevier
OBJECTIVE: Recently, the technique of high-resolution magnetic resonance imaging (HR-
MRI) has been developed to depict intracranial artery wall. We aimed to compare the vessel …

Middle cerebral artery intraplaque hemorrhage: prevalence and clinical relevance

WH Xu, ML Li, S Gao, J Ni, M Yao, LX Zhou… - Annals of …, 2012 - Wiley Online Library
Objective: Little is known about the composition of middle cerebral artery (MCA) plaques
and how they relate to clinical status. Using high‐resolution magnetic resonance imaging …

Critical cap thickness and rupture in symptomatic carotid plaques: the oxford plaque study

JN Redgrave, P Gallagher, JK Lovett, PM Rothwell - Stroke, 2008 - Am Heart Assoc
Background and Purpose—Advances in carotid plaque imaging could allow quantification of
fibrous cap thickness in vivo. While a cap thickness< 65 μm is the accepted definition of …

Imaging the vulnerable plaque

D Vancraeynest, A Pasquet, V Roelants… - Journal of the American …, 2011 - jacc.org
Cardiovascular diseases are still the primary causes of mortality in the United States and in
Western Europe. Arterial thrombosis is triggered by a ruptured atherosclerotic plaque and …

Determinants of magnetic resonance imaging detected carotid plaque components: the Rotterdam Study

QJA van den Bouwhuijsen, MW Vernooij… - European heart …, 2012 - academic.oup.com
Aims Components of carotid atherosclerotic plaque such as intraplaque haemorrhage and
lipid core are important determinants of plaque progression and destabilization. The …

[HTML][HTML] Carotid plaque imaging and the risk of atherosclerotic cardiovascular disease

G Zhu, J Hom, Y Li, B Jiang, F Rodriguez… - Cardiovascular …, 2020 - ncbi.nlm.nih.gov
Carotid artery plaque is a measure of atherosclerosis and is associated with future risk of
atherosclerotic cardiovascular disease (ASCVD), which encompasses coronary …

[PDF][PDF] Unstable carotid artery plaque: new insights and controversies in diagnostics and treatment

K Skagen, M Skjelland, M Zamani… - Croatian medical journal, 2016 - hrcak.srce.hr
Cardiovascular disease (CVD) is estimated to be the leading cause of death globally,
causing 14 million deaths each year (1). It is also the leading cause of long-term disability in …