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Patterning embryos with oscillations: structure, function and dynamics of the vertebrate segmentation clock
The segmentation clock is an oscillating genetic network thought to govern the rhythmic and
sequential subdivision of the elongating body axis of the vertebrate embryo into somites: the …
sequential subdivision of the elongating body axis of the vertebrate embryo into somites: the …
A comparative view on mechanisms and functions of skeletal remodelling in teleost fish, with special emphasis on osteoclasts and their function
Resorption and remodelling of skeletal tissues is required for development and growth,
mechanical adaptation, repair, and mineral homeostasis of the vertebrate skeleton. Here we …
mechanical adaptation, repair, and mineral homeostasis of the vertebrate skeleton. Here we …
The genetics and embryology of zebrafish metamerism
SA Holley - Developmental dynamics: an official publication of …, 2007 - Wiley Online Library
Somites are the most obvious metameric structures in the vertebrate embryo. They are
mesodermal segments that form in bilateral pairs flanking the notochord and are created …
mesodermal segments that form in bilateral pairs flanking the notochord and are created …
[HTML][HTML] A systematic genome-wide screen for mutations affecting organogenesis in Medaka, Oryzias latipes
M Furutani-Seiki, T Sasado, C Morinaga… - Mechanisms of …, 2004 - Elsevier
A large-scale mutagenesis screen was performed in Medaka to identify genes acting in
diverse developmental processes. Mutations were identified in homozygous F3 progeny …
diverse developmental processes. Mutations were identified in homozygous F3 progeny …
Cell rearrangements during development of the somite and its derivatives
C Kalcheim, R Ben-Yair - Current opinion in genetics & development, 2005 - Elsevier
The generation of somites, and the subsequent formation of their major derivatives, muscle-,
cartilage-, dermis-and tendon-cell lineages, is tightly orchestrated and, to different extents …
cartilage-, dermis-and tendon-cell lineages, is tightly orchestrated and, to different extents …
Species-specific roles of the Notch ligands, receptors, and targets orchestrating the signaling landscape of the segmentation clock
PS Ramesh, LF Chu - Frontiers in Cell and Developmental Biology, 2024 - frontiersin.org
Somitogenesis is a hallmark feature of all vertebrates and some invertebrate species that
involves the periodic formation of block-like structures called somites. Somites are transient …
involves the periodic formation of block-like structures called somites. Somites are transient …
[HTML][HTML] Zebrafish cypher is important for somite formation and heart development
DLM van der Meer, IJ Marques, JTD Leito, J Besser… - Developmental …, 2006 - Elsevier
Mammalian CYPHER (Oracle, KIA0613), a member of the PDZ-LIM family of proteins
(Enigma/LMP-1, ENH, ZASP/Cypher, RIL, ALP, and CLP-36), has been associated with …
(Enigma/LMP-1, ENH, ZASP/Cypher, RIL, ALP, and CLP-36), has been associated with …
Cell-autonomous timing drives the vertebrate segmentation clock's wave pattern
LA Rohde, A Bercowsky-Rama, G Valentin… - Elife, 2024 - elifesciences.org
Rhythmic and sequential segmentation of the growing vertebrate body relies on the
segmentation clock, a multi-cellular oscillating genetic network. The clock is visible as tissue …
segmentation clock, a multi-cellular oscillating genetic network. The clock is visible as tissue …
Comparative analysis of her genes during fish somitogenesis suggests a mouse/chick-like mode of oscillation in medaka
M Gajewski, H Elmasri, M Girschick, D Sieger… - Development genes and …, 2006 - Springer
Somitogenesis is the key developmental step, which divides the vertebrate body axis into
segmentally repeated structures. It requires an intricate process of pre-patterning, which is …
segmentally repeated structures. It requires an intricate process of pre-patterning, which is …
[HTML][HTML] tgfβ3 regulation of chondrogenesis and osteogenesis in zebrafish is mediated through formation and survival of a subpopulation of the cranial neural crest
Zebrafish tgfβ3 is strongly expressed in a subpopulation of the migrating neural crest cells,
develo** pharyngeal arches and neurocranial cartilages. To study the regulatory role of …
develo** pharyngeal arches and neurocranial cartilages. To study the regulatory role of …