Epidermal growth factor receptor (EGFR) plays a pivotal role in early brain development,
although its expression pattern declines in accordance with the maturation of the active …

Numerous molecular mechanisms are being examined in an attempt to discover disease-
modifying drugs to slow down the underlying neurodegeneration in Alzheimer's disease …

Amyotrophic lateral sclerosis (ALS) is a terminalneurodegenerative disease. Clinical and
molecular observations suggest that ALS pathology originates at a single site and spreads …

Uncontrolled accumulation of extracellular matrix leads to tissue fibrosis and loss of organ
function. We previously demonstrated in vitro that the DNA/RNA-binding protein fused in …

Pseudostellaria heterophylla, has historically been used as medicine food homology plant
for thousand years in China. Our previous studies had indicated that daily intake of …

Knockoff-based methods have become increasingly popular due to their enhanced power
for locus discovery and their ability to prioritize putative causal variants in a genome-wide …

Epidermal growth factor receptor (EGFR) signaling plays a substantial role in learning and
memory. The upregulation of EGFR has been embroiled in the pathophysiology of …

ERBB receptor tyrosine kinases are involved in development and diseases like cancer,
cardiovascular, neurodevelopmental, and mental disorders. Although existing drugs target …

Thyroid hormones (TH) are vital for brain functions, while TH deficiency, ie hypothyroidism,
induces neurological impairment in children and adults. Cerebellar neuronal apoptosis and …

Alzheimer's disease is the most common form of dementia. Notwithstanding the huge
investments in drug development, only one disease-modifying treatment has been recently …