Simple Summary Diffuse midline glioma (DMG), especially diffuse intrinsic pontine glioma
(DIPG), is a deadly pediatric brain tumor that is difficult to diagnose and lacks any real …

Pediatric low grade brain tumors and neurodevelopmental disorders share proteins,
signaling pathways, and networks. They also share germline mutations and an impaired …

Background Neurodevelopmental disorders increase brain tumor risk, suggesting that
normal brain development may have protective properties. Mutations in epigenetic …

High-grade gliomas (HGG) are deadly diseases for both adult and pediatric patients.
Recently, it has been shown that neuronal activity promotes the progression of multiple …

Diffuse midline glioma (DMG) is a type of lethal brain tumor that develops mainly in children.
The majority of DMG harbor the K27M mutation in histone H3. Oligodendrocyte progenitor …

High-grade glioma (HGG) is the most common cause of cancer death in children and the
most common primary central nervous system tumor in adults. While pediatric HGG was …

Simple Summary Diffuse midline glioma (DMG) is a devastating pediatric brain tumor with
urgent unmet need for novel treatment modalities. LIN28B RNA binding protein is …

Purpose To establish an individualized predictive model to identify patients with brainstem
gliomas (BSGs) at high risk of H3K27M mutation, with the inclusion of brain structural …

Simple Summary Pediatric high-grade gliomas are aggressive and deadly brain tumors that
arise in children and are notoriously difficult to cure. Researchers require accurate methods …

Diffuse midline glioma H3 K27M-altered is a recently renamed high-grade glioma in the
2021 World Health Organization (WHO) Classification of Central Nervous System Tumors …