Gut microbiota and rheumatoid arthritis: From pathogenesis to novel therapeutic opportunities

T Zhao, Y Wei, Y Zhu, Z **e, Q Hai, Z Li… - Frontiers in …, 2022 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic autoimmune disease that primarily affects the joints.
Microbial infection is considered a crucial inducer of RA. Alterations in the composition of …

The microbiome in autoimmune diseases

F De Luca, Y Shoenfeld - Clinical & Experimental Immunology, 2019 - academic.oup.com
The microbiome is represented by microorganisms which live in a symbiotic way with the
mammalian. Microorganisms have the ability to influence different physiological aspects …

The promise of the gut microbiome as part of individualized treatment strategies

DA Schupack, RAT Mars, DH Voelker… - Nature reviews …, 2022 - nature.com
Variability in disease presentation, progression and treatment response has been a central
challenge in medicine. Although variability in host factors and genetics are important, it has …

Gut commensal Parabacteroides distasonis alleviates inflammatory arthritis

H Sun, Y Guo, H Wang, A Yin, J Hu, T Yuan, S Zhou… - Gut, 2023 - gut.bmj.com
Objective Gut microbiota dysbiosis is closely linked to the pathogenesis of rheumatoid
arthritis (RA). We aimed to identify potential probiotic gut microbes that can ameliorate the …

Generation of regulatory dendritic cells and CD4+Foxp3+ T cells by probiotics administration suppresses immune disorders

HK Kwon, CG Lee, JS So, CS Chae… - Proceedings of the …, 2010 - National Acad Sciences
The beneficial effects of probiotics have been described in many diseases, but the
mechanism by which they modulate the immune system is poorly understood. In this study …

Probiotics and immunity

AT Borchers, C Selmi, FJ Meyers, CL Keen… - Journal of …, 2009 - Springer
Probiotics are defined as live microorganisms that, when administered in adequate
amounts, confer a health benefit on the host, including the gastrointestinal tract. While this …

Analysis of gut microbiota in rheumatoid arthritis patients: disease-related dysbiosis and modifications induced by etanercept

A Picchianti-Diamanti, C Panebianco, S Salemi… - International journal of …, 2018 - mdpi.com
A certain number of studies were carried out to address the question of how dysbiosis could
affect the onset and development of rheumatoid arthritis (RA), but little is known about the …

[HTML][HTML] Gut microbiota in pre-clinical rheumatoid arthritis: From pathogenesis to preventing progression

L Lin, K Zhang, Q **ong, J Zhang, B Cai, Z Huang… - Journal of …, 2023 - Elsevier
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by progressive
polyarthritis that leads to cartilage and bone damage. Pre-clinical RA is a prolonged state …

A novel probiotic mixture exerts a therapeutic effect on experimental autoimmune encephalomyelitis mediated by IL-10 producing regulatory T cells

S Lavasani, B Dzhambazov, M Nouri, F Fåk, S Buske… - PloS one, 2010 - journals.plos.org
Background Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the
central nervous system (CNS). One potential therapeutic strategy for MS is to induce …

Modulating the microbiota as a therapeutic intervention for type 2 diabetes

MN Huda, M Kim, BJ Bennett - Frontiers in endocrinology, 2021 - frontiersin.org
Mounting evidence suggested that the gut microbiota has a significant role in the
metabolism and disease status of the host. In particular, Type 2 Diabetes (T2D), which has a …