▪ Abstract Converging findings of animal and human studies provide compelling evidence
that the amygdala is critically involved in enabling us to acquire and retain lasting memories …

Our memories are not all created equally strong: Some experiences are well remembered
while others are remembered poorly, if at all. Research on memory modulation investigates …

Scopolamine is used as a standard/reference drug for inducing cognitive deficits in healthy
humans and animals. Effects are often interpreted in terms of a role of acetylcholine in …

Using a paradigm known as fear-potentiated startle, we have examined the neurobiological
substrates of Pavlovian fear conditioning. In these experiments, rats are trained to fear an …

The amygdala has long been known to play a key role in supporting memory for emotionally
arousing experiences. For example, classical fear conditioning depends on neural plasticity …

Examining the positive and negative pictures separately revealed that emotionally
enhanced memory (EEM) for positive pictures was mediated by attention, with no significant …

Emotion has been shown to have a modulatory effect on declarative memory. Normal aging
is associated with a decline in declarative memory, but whether aging might affect the …

The central cholinergic system and muscarinic cholinergic receptor (mR) activation have
long been associated with cognitive function. Although mR activation is no doubt involved in …

The basolateral amygdala (BLA) can influence distinct learning and memory formation.
Hippocampal long-term potentiation (LTP), the most prominent cellular model of memory …

According to the consolidation hypothesis, enhanced memory for emotional information
reflects the modulatory effect of the amygdala on the medial temporal lobe (MTL) memory …