DNA damage is correlated with and may drive the ageing process. Neurons in the brain are
postmitotic and are excluded from many forms of DNA repair; therefore, neurons are …

DNA double-strand breaks (DSBs) are deleterious lesions that are generated in response to
ionizing radiation or replication fork collapse that can lead to genomic instability and cancer …

Mesenchymal stromal cells (MSCs) are heterogeneous and contain several populations,
including stem cells. MSCs' secretome has the ability to induce proliferation, differentiation …

Non-coding RNAs play a crucial role in maintaining genomic stability which is essential for
cell survival and preventing tumorigenesis. Through an extensive crosstalk between non …

Background: Ataxia telangiectasia mutated (ATM) is a kinase that has a central role in the
maintenance of genomic integrity by activating cell cycle checkpoints and promoting repair …

The inability of cancer cells in taking care of DNA damages can lead to cancer development
and/or progression. Due to the essential role of DNA repair in maintaining genomic stability …

MicroRNAs (miRNAs) are believed to be resistant against radiotherapy in certain types of
cancers. The aim of our study was to determine the clinical application of miRNAs in non …

MicroRNAs (miRNA) are small, non-coding, RNAs with gene expression regulator roles. As
an important class of regulators of many cellular pathways, miRNAs are involved in many …

Pinostrobin (PN) is the most abundant flavonoid found in fingerroot. Although the anti-
leukemic properties of PN have been reported, its mechanisms are still unclear. MicroRNAs …

Purpose Radiogenomics is the study of genomic changes that underlie the radioresponse of
normal and tumor tissues. And while this is generally regarded as a whole genome …