Changing demography and the challenge of dementia in India

V Ravindranath, JS Sundarakumar - Nature Reviews Neurology, 2021 - nature.com
In India, increasing lifespan and decreasing fertility rates have resulted in a growing number
of older persons. By 2050, people over 60 years of age are predicted to constitute 19.1% of …

Vascular dementia and underlying sex differences

F Akhter, A Persaud, Y Zaokari, Z Zhao… - Frontiers in aging …, 2021 - frontiersin.org
Vascular dementia (VaD) is the second most common form of dementia after Alzheimer's
disease (AD); where Alzheimer's accounts for 60–70% of cases of dementia and VaD …

Major pathogenic mechanisms in vascular dementia: Roles of cellular stress response and hormesis in neuroprotection

V Calabrese, J Giordano, A Signorile… - Journal of …, 2016 - Wiley Online Library
Vascular dementia (VaD), considered the second most common cause of cognitive
impairment after Alzheimer disease in the elderly, involves the impairment of memory and …

Paraoxonase role in human neurodegenerative diseases

CO Reichert, D Levy, SP Bydlowski - Antioxidants, 2020 - mdpi.com
The human body has biological redox systems capable of preventing or mitigating the
damage caused by increased oxidative stress throughout life. One of them are the …

Genetics of vascular dementia: systematic review and meta-analysis

JH Sun, L Tan, HF Wang, MS Tan… - Journal of …, 2015 - content.iospress.com
Background: Vascular dementia (VaD) is the second most common type of dementia. So far,
little is known about the contribution of genetic polymorphisms to the risk of VaD. Many …

[HTML][HTML] Genetic architecture of common non-Alzheimer's disease dementias

R Guerreiro, E Gibbons, M Tábuas-Pereira… - Neurobiology of …, 2020 - Elsevier
Frontotemporal dementia (FTD), dementia with Lewy bodies (DLB) and vascular dementia
(VaD) are the most common forms of dementia after Alzheimer's disease (AD). The …

Genetics and underlying pathology of dementia

B Ferencz, L Gerritsen - Neuropsychology review, 2015 - Springer
As the population steadily ages, dementia, in all its forms, remains a great societal
challenge. Yet, our knowledge of their etiology remains rather limited. To this end, genetic …

Genetics of vascular dementia–review from the ICVD working group

MA Ikram, A Bersano, R Manso-Calderón, JP Jia… - BMC medicine, 2017 - Springer
Background Vascular dementia is a common disorder resulting in considerable morbidity
and mortality. Determining the extent to which genes play a role in disease susceptibility and …

Organophosphate pesticides and PON1 L55M in Parkinson's disease progression

KC Paul, JS Sinsheimer, M Cockburn… - Environment …, 2017 - Elsevier
Background Parkinson's disease (PD) has motor and non-motor features that contribute to
its phenotype and functional decline. Organophosphate (OP) pesticides and PON1 L55M …

Serum paraoxonase and arylesterase activities of paraoxonase‐1 (PON‐1), mild cognitive impairment, and 2‐year conversion to dementia: A pilot study

C Cervellati, A Trentini, A Romani… - Journal of …, 2015 - Wiley Online Library
Converging lines of evidence suggest that paraoxonase‐1 (PON‐1) may confer protection
against inflammatory and oxidative challenge which, in turn, plays a key‐role in the onset …