Abstract Simulated Moving Bed or SMB chromatography is a continuous adsorption
technique that increases throughput, purity and yield relative to batch chromatography. SMB …

In this work, a procedure for the separation of a racemic mixture of guaifenesin onto a chiral
stationary phase (Chiralpak AD), by means of Simulated Moving Bed (SMB) technology, is …

In the production of a human therapeutic protein from inclusion bodies, product related
impurities of very similar size and charge to the product are created as byproducts of the …

Bupivacaine is an amide type local anesthetic widely used in surgery and obstetrics
because of its sustained peripheral and central nerve blockade. R-(+)-bupivacaine is more …

The use of chromatographic techniques to obtain significant quantities of enantiomerically
pure drug intermediates is well established. With respect to batchwise preparative …

In the present work a mathematical model has been presented to study the behaviour of five‐
zone simulating moving bed (SMB) system for the separation of a ternary mixture of certain …

A stepwise model with lumped mass transfer kinetics (SW‐LM) is applied for
chromatographic column modeling in simulated moving bed (SMB) separation of a racemic …

A semipreparative column packed with microcrystalline cellulose triacetate (MCTA) was
used to separate ketamine enantiomers by high‐performance liquid chromatography …

There is great interest nowadays in the use of preparative liquid chromatography as an
effective tool for the production of enantiomerically pure, or enriched, compounds for the …

In this study, the binary and the ternary phase diagrams of R-/S-ketamine were determined
based on differential scanning calorimetry (DSC) measurements. The binary phase diagram …