The genetically informed neurobiology of addiction (GINA) model

R Bogdan, AS Hatoum, EC Johnson… - Nature Reviews …, 2023 - nature.com
Addictions are heritable and unfold dynamically across the lifespan. One prominent
neurobiological theory proposes that substance-induced changes in neural circuitry promote …

Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders

AS Hatoum, SMC Colbert, EC Johnson… - Nature Mental …, 2023 - nature.com
Genetic liability to substance use disorders can be parsed into loci that confer general or
substance-specific addiction risk. We report a multivariate genome-wide association meta …

[HTML][HTML] Substance use patterns in 9 to 13-year-olds: Longitudinal findings from the Adolescent Brain Cognitive Development (ABCD) study

RM Sullivan, NE Wade, AL Wallace, SF Tapert… - Drug and alcohol …, 2022 - Elsevier
Background Though largely substance-naïve at enrollment, a proportion of the youth in the
Adolescent Brain Cognitive Development (ABCD) Study are expected to initiate substance …

[HTML][HTML] Why weight? Analytic approaches for large-scale population neuroscience data

AM Gard, LW Hyde, SG Heeringa, BT West… - Developmental …, 2023 - Elsevier
Population-based neuroimaging studies that feature complex sampling designs enable
researchers to generalize their results more widely. However, several theoretical and …

[HTML][HTML] Longitudinal Analysis of the ABCD® Study

SW Hawes, AK Littlefield, DA Lopez, KJ Sher… - Developmental …, 2025 - Elsevier
Abstract The Adolescent Brain Cognitive Development®(ABCD) Study provides a unique
opportunity to investigate developmental processes in a large, diverse cohort of youths …

Substance use onset in high-risk 9–13 year-olds in the ABCD study

NE Wade, SF Tapert, KM Lisdahl, MA Huestis… - Neurotoxicology and …, 2022 - Elsevier
Aim A key aim of the Adolescent Brain Cognitive Development℠(ABCD) Study is to
document substance use onset, patterns, and sequelae across adolescent development …

Mobile phone ownership, social media use, and substance use at ages 11–13 in the ABCD study

N Doran, NE Wade, KE Courtney, RM Sullivan… - Addictive Behaviors, 2025 - Elsevier
Introduction There is ongoing concern about the impact of increasing use of social media
and digital devices on unhealthy behaviors such as substance use in youth. Mobile phone …

Prenatal Cannabis and Tobacco Co-Exposure and Its Association with Behavioural Outcomes in Middle Childhood: Co-exposition prénatale au cannabis et au tabac …

E Nadler, J Jacobus, RA Rabin - The Canadian Journal of …, 2025 - journals.sagepub.com
Résumé Objectifs La légalisation du cannabis a provoqué une augmentation de l'usage
prénatal du cannabis. Étant donné que le tabac est communément co-utilisé avec le …

The beneficial effect of sleep on behavioral health problems in youth is disrupted by prenatal cannabis exposure: A causal random forest analysis of Adolescent Brain …

PA Spechler, RM Gutierrez, SF Tapert… - Child …, 2023 - Wiley Online Library
Studies suggest prenatal cannabis exposure is associated with mood/behavioral problems
in children. However, it is unclear if targeting modifiable domains like sleep behaviors would …

[HTML][HTML] Individual-, peer-, and parent-level substance use-related factors among 9-and 10-year-olds from the ABCD Study: Prevalence rates and sociodemographic …

ME Martz, MM Heitzeg, KM Lisdahl, CC Cloak… - Drug and alcohol …, 2022 - Elsevier
Background Although a relatively large body of research has identified multiple factors
associated with adolescent substance use, less is known about earlier substance-related …