Biocatalysis: enzymatic synthesis for industrial applications

S Wu, R Snajdrova, JC Moore… - Angewandte Chemie …, 2021 - Wiley Online Library
Biocatalysis has found numerous applications in various fields as an alternative to chemical
catalysis. The use of enzymes in organic synthesis, especially to make chiral compounds for …

Biocatalysis: A pharma perspective

JP Adams, MJB Brown… - Advanced Synthesis …, 2019 - Wiley Online Library
Biocatalysis over the past few years has matured into an essential tool for modern, cost
effective and sustainable pharmaceutical manufacturing. While some reaction classes are …

Novozym 435: the “perfect” lipase immobilized biocatalyst?

C Ortiz, ML Ferreira, O Barbosa… - Catalysis Science & …, 2019 - pubs.rsc.org
Novozym 435 (N435) is a commercially available immobilized lipase produced by
Novozymes. It is based on immobilization via interfacial activation of lipase B from Candida …

Biocatalytic amide bond formation

M Lubberink, W Finnigan, SL Flitsch - Green Chemistry, 2023 - pubs.rsc.org
Amide bonds occur in over half of target compounds in medicinal chemistry patents, making
amide bond formation the most commonly performed reaction in the pharmaceutical …

Taguchi design-assisted co-immobilization of lipase A and B from Candida antarctica onto chitosan: Characterization, kinetic resolution application, and docking …

KS Moreira, ALB de Oliveira… - … Research and Design, 2022 - Elsevier
In the present communication, the simultaneous co-immobilization by covalent binding of
lipase A from Candida antarctica (CALA) and lipase B from Candida antarctica (CALB) in …

GreenMedChem: the challenge in the next decade toward eco-friendly compounds and processes in drug design

C Castiello, P Junghanns, A Mergel, C Jacob… - Green …, 2023 - pubs.rsc.org
Green chemistry has become a hot topic and the focus of not only many companies but also
researchers. Green chemistry strives to identify alternative and environmentally friendly …

Enzymatic late‐stage modifications: better late than never

E Romero, BS Jones, BN Hogg… - Angewandte Chemie …, 2021 - Wiley Online Library
Enzyme catalysis is gaining increasing importance in synthetic chemistry. Nowadays, the
growing number of biocatalysts accessible by means of bioinformatics and enzyme …

Microbial lipase production: A deep insight into the recent advances of lipase production and purification techniques

S Fatima, A Faryad, A Ataa, FA Joyia… - Biotechnology and …, 2021 - Wiley Online Library
Importance of enzymes is ever‐rising particularly microbial lipases holding great industrial
worth owing to their potential to catalyze a diverse array of chemical reactions in aqueous as …

Amide bond formation via aerobic photooxidative coupling of aldehydes with amines catalyzed by a riboflavin derivative

A Hassan Tolba, M Krupicka, J Chudoba… - Organic …, 2021 - ACS Publications
We report an effective, operationally simple, and environmentally friendly system for the
synthesis of tertiary amides by the oxidative coupling of aromatic or aliphatic aldehydes with …

An appraisal on prominent industrial and biotechnological applications of bacterial lipases

F Akram, AS Mir, I Haq, A Roohi - Molecular biotechnology, 2023 - Springer
Microbial lipases expedite the hydrolysis and synthesis of long-chain acyl esters. They are
highly significant commercial biocatalysts to biotechnologists and organic chemists. The …