30 years of second-generation antiseizure medications: impact and future perspectives

E Perucca, MJ Brodie, P Kwan, T Tomson - The Lancet Neurology, 2020 - thelancet.com
Summary Since 1989, 18 second-generation antiseizure medications have reached the
market, resulting in a greatly increased range of treatment options for patients and …

Impact of predictive, preventive and precision medicine strategies in epilepsy

R Nabbout, M Kuchenbuch - Nature Reviews Neurology, 2020 - nature.com
Over the last decade, advances in genetics, neuroimaging and EEG have enabled the
aetiology of epilepsy to be identified earlier in the disease course than ever before. At the …

Brain 18F-FDG PET for the diagnosis of autoimmune encephalitis: a systematic review and a meta-analysis

M Bordonne, MB Chawki, M Doyen, A Kas… - European journal of …, 2021 - Springer
Objective To consolidate current understanding of detection sensitivity of brain 18 F-FDG
PET scans in the diagnosis of autoimmune encephalitis and to define specific metabolic …

Paraneoplastic neurologic disorders

M Gilligan, C McGuigan, A McKeon - Current neurology and neuroscience …, 2023 - Springer
Abstract Purpose of Review To provide an overview and highlight recent updates in the field
of paraneoplastic neurologic disorders. Recent Findings The prevalence of paraneoplastic …

Focal epilepsies: update on diagnosis and classification

FA Nascimento, D Friedman, JM Peters… - Epileptic …, 2023 - Wiley Online Library
Correctly diagnosing and classifying seizures and epilepsies is paramount to ensure the
delivery of optimal care to patients with epilepsy. Focal seizures, defined as those that …

Paraneoplastic neurological syndromes: clinical presentations and management

MF Devine, N Kothapalli, M Elkhooly… - Therapeutic …, 2021 - journals.sagepub.com
We provide an overview of the varied presentations of paraneoplastic neurological
syndromes. We also review the onconeural antibodies and their particular oncological and …

Generative adversarial network and convolutional neural network-based EEG imbalanced classification model for seizure detection

B Gao, J Zhou, Y Yang, J Chi, Q Yuan - Biocybernetics and Biomedical …, 2022 - Elsevier
Automatic seizure detection technology is of great significance to reduce workloads of
neurologists for epilepsy diagnosis and treatments. Imbalanced classification is a challenge …

A practical approach to in-hospital management of new-onset refractory status epilepticus/febrile infection related epilepsy syndrome

Z Sheikh, LJ Hirsch - Frontiers in Neurology, 2023 - frontiersin.org
New-onset refractory status epilepticus (NORSE) is “a clinical presentation, not a specific
diagnosis, in a patient without active epilepsy or other preexisting relevant neurological …

Microglia and infiltrating macrophages in ictogenesis and epileptogenesis

S Bröer, A Pauletti - Frontiers in Molecular Neuroscience, 2024 - frontiersin.org
Phagocytes maintain homeostasis in a healthy brain. Upon injury, they are essential for
repairing damaged tissue, recruiting other immune cells, and releasing cytokines as the first …

[HTML][HTML] Immunity, ion channels and epilepsy

TS Chen, MC Lai, HYI Huang, SN Wu… - International journal of …, 2022 - mdpi.com
Epilepsy is a common chronic neurological disorder in modern society. One of the major
unmet challenges is that current antiseizure medications are basically not disease …