Functions of macrophage colony-stimulating factor (CSF1) in development, homeostasis, and tissue repair

A Sehgal, KM Irvine, DA Hume - Seminars in immunology, 2021 - Elsevier
Macrophage colony-stimulating factor (CSF1) is the primary growth factor required for the
control of monocyte and macrophage differentiation, survival, proliferation and renewal …

M-CSFR/CSF1R signaling regulates myeloid fates in zebrafish via distinct action of its receptors and ligands

M Hason, T Mikulasova, O Machonova… - Blood …, 2022 - ashpublications.org
Macrophage colony-stimulating factor receptor (M-CSFR/CSF1R) signaling is crucial for the
differentiation, proliferation, and survival of myeloid cells. The CSF1R pathway is a …

[HTML][HTML] Regulation and function of macrophage colony-stimulating factor (CSF1) in the chicken immune system

Z Wu, R Harne, C Chintoan-Uta, TJ Hu… - Developmental & …, 2020 - Elsevier
Macrophage colony-stimulating factor (CSF1) is an essential growth factor to control the
proliferation, differentiation and survival of cells of the macrophage lineage in vertebrates …

CSF1R defines the mononuclear phagocyte system lineage in human blood in health and COVID-19

TW Combes, F Orsenigo, A Stewart… - Immunotherapy …, 2021 - academic.oup.com
Mononuclear phagocytes defend tissues, present antigens, and mediate recovery and
healing. To date, we lack a marker to unify mononuclear phagocytes in humans or that …

Ki20227 aggravates apoptosis, inflammatory response, and oxidative stress after focal cerebral ischemia injury

C Jiang, ZN Wang, YC Kang, Y Chen… - Neural Regeneration …, 2022 - journals.lww.com
The survival of microglia depends on the colony-stimulating factor-1 receptor (CSF1R)
signaling pathway under physiological conditions. Ki20227 is a highly selective CSF1R …

Macrophages and dendritic cells

K Sutton, A Balic, B Kaspers, L Vervelde - Avian immunology, 2022 - Elsevier
Macrophages, monocytes, and conventional dendritic cells (cDCs), together with B
lymphocytes, are termed antigen-presenting cells (APCs). Monocytes and cDCs differentiate …

Squamous cell carcinoma is associated with reduced IL34 expression, alterations in the Langerhans cell antigen‐processing‐presentation machinery and poor …

TVT Dang, KR Gillinder, Q Nguyen… - Clinical & …, 2024 - Wiley Online Library
Abstract Objectives Langerhans cells (LCs) are epithelial antigen‐presenting cells (APC)
contributing to immune surveillance. LCs depend on interleukin 34 (IL34) production by …

Measurement of serum Interleukin 34 (IL‐34) and correlation with severity and pruritus scores in client‐owned dogs with atopic dermatitis

DJ Gow, H Jackson, P Forsythe, T Nuttall… - Veterinary …, 2020 - Wiley Online Library
Background Atopic dermatitis (AD) is a common inflammatory skin disease of dogs.
Interleukin (IL)‐34 is a monocyte/macrophage growth factor, produced mainly by …

Analysis of the progeny of sibling matings reveals regulatory variation impacting the transcriptome of immune cells in commercial chickens

L Freem, KM Summers, AA Gheyas, A Psifidi… - Frontiers in …, 2019 - frontiersin.org
There is increasing recognition that the underlying genetic variation contributing to complex
traits influences transcriptional regulation and can be detected at a population level as …

Mutation in the rat interleukin 34 gene impacts macrophage development, homeostasis and inflammation in the brain and periphery

S Huang, OL Patkar, S Schulze, D Carter-Cusack… - bioRxiv, 2025 - biorxiv.org
Interleukin-34 (IL34) and colony stimulating factor 1 (CSF1) signal through a shared receptor
(CSF1R) to control macrophage survival, differentiation and function. Here we describe the …