As one of the most abundant and conserved RNA species, transfer RNAs (tRNAs) are well
known for their role in reading the codons on messenger RNAs and translating them into …

Background Genome simplification is an important topic in the field of life sciences that has
attracted attention from its conception to the present day. It can help uncover the essential …

The Sc2. 0 project is building a eukaryotic synthetic genome from scratch. A major milestone
has been achieved with all individual Sc2. 0 chromosomes assembled. Here, we describe …

Here, we report the design, construction, and characterization of a tRNA neochromosome, a
designer chromosome that functions as an additional, de novo counterpart to the native …

Heterochromatic loci can exhibit different transcriptional states in genetically identical cells.
A popular model posits that the inheritance of modified histones is sufficient for inheritance …

Transfer RNAs (tRNAs) are well known for their essential function as adapters in delivering
amino acids to ribosomes and making the link between mRNA and protein according to the …

Natural isolates of the potato and tomato pathogen Phytophthora infestans exhibit
substantial variation in virulence, chemical sensitivity, ploidy, and other traits. A chromosome …

Cellular tRNAs appear today as a diverse population of informative macromolecules with
conserved general elements ensuring essential common functions and different and …

SUMMARY PlantRNA (http://plantrna. ibmp. cnrs. fr/) is a comprehensive database of
transfer RNA (tRNA) gene sequences retrieved from fully annotated nuclear, plastidial and …

Gene expression in Saccharomyces cerevisiae is regulated at multiple levels. Genomic and
epigenomic map** of transcription factors and chromatin factors has led to the delineation …