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Reaching an evidence-based prognosis for personalized treatment of multiple sclerosis
Personalized treatment is ideal for multiple sclerosis (MS) owing to the heterogeneity of
clinical features, but current knowledge gaps, including validation of biomarkers and …
clinical features, but current knowledge gaps, including validation of biomarkers and …
Imaging retina to study dementia and stroke
With increase in life expectancy, the number of persons suffering from common age-related
brain diseases, including neurodegenerative (eg, dementia) and cerebrovascular (eg …
brain diseases, including neurodegenerative (eg, dementia) and cerebrovascular (eg …
Optical coherence tomography reflects brain atrophy in multiple sclerosis: a four‐year study
Objective The aim of this work was to determine whether atrophy of specific retinal layers
and brain substructures are associated over time, in order to further validate the utility of …
and brain substructures are associated over time, in order to further validate the utility of …
Optical coherence tomography in multiple sclerosis: a 3‐year prospective multicenter study
Objective To evaluate changes over 3 years in the thickness of inner retinal layers including
the peripapillary retinal nerve fiber layer (pRNFL), and combined macular ganglion cell and …
the peripapillary retinal nerve fiber layer (pRNFL), and combined macular ganglion cell and …
Retinal ganglion cell analysis using high-definition optical coherence tomography in patients with mild cognitive impairment and Alzheimer's disease
Background: Alzheimer's disease (AD) is a neurodegenerative disorder with emerging
evidence that it is associated with retinal ganglion cell loss; however, few data exist to …
evidence that it is associated with retinal ganglion cell loss; however, few data exist to …
Optical coherence tomography in multiple sclerosis
J Britze, JL Frederiksen - Eye, 2018 - nature.com
To summarize recent findings regarding the utility of optical coherence tomography in
multiple sclerosis. We searched PubMed for relevant articles using the keywords 'optical …
multiple sclerosis. We searched PubMed for relevant articles using the keywords 'optical …
Vision and vision-related outcome measures in multiple sclerosis
Visual impairment is a key manifestation of multiple sclerosis. Acute optic neuritis is a
common, often presenting manifestation, but visual deficits and structural loss of retinal …
common, often presenting manifestation, but visual deficits and structural loss of retinal …
Retinal thickness measured with optical coherence tomography and risk of disability worsening in multiple sclerosis: a cohort study
EH Martinez-Lapiscina, S Arnow, JA Wilson… - The Lancet …, 2016 - thelancet.com
Background Most patients with multiple sclerosis without previous optic neuritis have thinner
retinal layers than healthy controls. We assessed the role of peripapillary retinal nerve fibre …
retinal layers than healthy controls. We assessed the role of peripapillary retinal nerve fibre …
Optimal intereye difference thresholds by optical coherence tomography in multiple sclerosis: an international study
Objective To determine the optimal thresholds for intereye differences in retinal nerve fiber
and ganglion cell+ inner plexiform layer thicknesses for identifying unilateral optic nerve …
and ganglion cell+ inner plexiform layer thicknesses for identifying unilateral optic nerve …
[HTML][HTML] Schizophrenia and the eye
Although visual processing impairments are common in schizophrenia, it is not clear to what
extent these originate in the eye vs. the brain. This review highlights potential contributions …
extent these originate in the eye vs. the brain. This review highlights potential contributions …