Despite achieving great public health strides to control tuberculosis (TB) within the United
States, it remains an enormous public health issue worldwide. Accurate statistics on …

Tuberculous meningitis disproportionately affects young children. As the most devastating
form of tuberculosis, it is associated with unacceptably high rates of mortality and morbidity …

Summary Background After infection with Mycobacterium tuberculosis, children are at an
increased risk of progression to tuberculosis disease; a condition that can be challenging to …

Background Many children who develop tuberculosis are thought to be missed by diagnostic
and reporting systems. We aimed to estimate paediatric tuberculosis incidence and …

The global burden of disease study—which has been affiliated with the World Bank and the
World Health Organisation (WHO) and is now housed in the Institute for Health Metrics and …

Abstract In 2015, the World Health Organization (WHO) declared tuberculosis (TB) to be
responsible for more deaths than any other single infectious disease. The burden of TB …

Early diagnosis of tuberculosis (TB), followed by effective treatment, is the cornerstone of
global TB control efforts. An estimated 3 million cases of TB remain undetected each year …

Introduction In high TB burden settings, it is estimated that 10–20% of total notifications
should be children, however, currently only 6–8% of the total TB notifications in Zambia are …

Background Understanding tuberculosis epidemiology among children and adolescents
informs treatment and prevention efforts, and efforts to eliminate disparities in tuberculosis …

Background: Clinical presentation for extrapulmonary tuberculosis (EPTB) in children can be
variable and nonspecific, leading to delayed diagnosis, disease and death. We describe the …