Overview of the 2022 WHO classification of thyroid neoplasms

ZW Baloch, SL Asa, JA Barletta, RA Ghossein… - Endocrine …, 2022 - Springer
This review summarizes the changes in the 5th edition of the WHO Classification of
Endocrine and Neuroendocrine Tumors that relate to the thyroid gland. The new …

Papillary thyroid cancer—Aggressive variants and impact on management: A narrative review

A Coca-Pelaz, JP Shah, JC Hernandez-Prera… - Advances in …, 2020 - Springer
Introduction Aggressive variants of papillary thyroid cancer (PTC) have been described with
increasing frequency. These variants include diffuse sclerosing variant, tall cell variant …

Do aggressive variants of papillary thyroid carcinoma have worse clinical outcome than classic papillary thyroid carcinoma?

E Song, MJ Jeon, HS Oh, M Han, YM Lee… - European Journal of …, 2018 - academic.oup.com
Objective Evidence for unfavorable outcomes of each type of aggressive variant papillary
thyroid carcinoma (AV-PTC) is not clear because most previous studies are focused on tall …

Oncocytic change in thyroid pathology

SL Asa, O Mete - Frontiers in Endocrinology, 2021 - frontiersin.org
Oncocytes are cells that have abundant eosinophilic cytoplasm due to the accumulation of
mitochondria; they are also known as oxyphils. In the thyroid they have been called Hürthle …

Tall cell variant of papillary thyroid carcinoma: impact of change in WHO definition and molecular analysis

KS Wong, SE Higgins, E Marqusee, MA Nehs… - Endocrine …, 2019 - Springer
The morphologic criteria for tall cell variant (TCV) of papillary thyroid carcinoma (PTC) were
modified in the 2017 WHO Classification of Tumors of Endocrine Organs, with a decrease in …

A deep learning–based algorithm for tall cell detection in papillary thyroid carcinoma

S Stenman, N Linder, M Lundin, C Haglund, J Arola… - PLoS …, 2022 - journals.plos.org
Introduction According to the World Health Organization, the tall cell variant (TCV) is an
aggressive subtype of papillary thyroid carcinoma (PTC) comprising at least 30% epithelial …

Tall cell percentage alone in PTC without aggressive features should not guide patients' clinical management

AM Poma, D Viola, E Macerola, A Proietti… - The Journal of …, 2021 - academic.oup.com
Context Recent diagnostic criteria updates of the tall cell variant of papillary thyroid
carcinoma (TCPTC) by the World Health Organization (WHO) have determined the inclusion …

Papillary thyroid carcinoma with tall cell features is as aggressive as tall cell variant: a meta-analysis

HG Vuong, NP Long, NH Anh, TD Nghi… - Endocrine …, 2018 - ec.bioscientifica.com
There are still ongoing debates as to which cut-off percentage of tall cell (TC) should be
used to define tall cell variant (TCV) papillary thyroid carcinoma (PTC). In this meta-analysis …

Papillary thyroid carcinoma tall cell variant shares accumulation of mitochondria, mitochondrial DNA mutations, and loss of oxidative phosphorylation complex I …

O Tsybrovskyy, M De Luise, D de Biase… - The Journal of …, 2022 - Wiley Online Library
Papillary thyroid carcinoma tall cell variant (PTC‐TCV), a form of PTC regarded as an
aggressive subtype, shares several morphologic features with oncocytic tumors. Pathogenic …

Prognostic parameters in differentiated thyroid carcinomas

NA Cipriani - Surgical Pathology Clinics, 2019 - surgpath.theclinics.com
Differentiated thyroid carcinomas make up most thyroid malignancies. The AJCC staging
system and the ATA risk prediction system are the best predictors of mortality and …