Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases

JS Loh, WQ Mak, LKS Tan, CX Ng, HH Chan… - Signal transduction and …, 2024 - nature.com
The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …

The impact of the gut microbiome on extra-intestinal autoimmune diseases

E Miyauchi, C Shimokawa, A Steimle… - Nature Reviews …, 2023 - nature.com
The prevalence of autoimmune diseases (ADs) worldwide has rapidly increased over the
past few decades. Thus, in addition to the classical risk factors for ADs, such as genetic …

Synergy and oxygen adaptation for development of next-generation probiotics

MT Khan, C Dwibedi, D Sundh, M Pradhan, JD Kraft… - Nature, 2023 - nature.com
The human gut microbiota has gained interest as an environmental factor that may
contribute to health or disease. The development of next-generation probiotics is a …

The gut microbiota in inflammatory bowel disease

P Qiu, T Ishimoto, L Fu, J Zhang, Z Zhang… - Frontiers in cellular and …, 2022 - frontiersin.org
Epidemiological surveys indicate that the incidence of inflammatory bowel disease (IBD) is
increasing rapidly with the continuous growth of the economy. A large number of studies …

The gut microbiota contributes to the pathogenesis of anorexia nervosa in humans and mice

Y Fan, RK Støving, S Berreira Ibraim… - Nature …, 2023 - nature.com
Anorexia nervosa (AN) is an eating disorder with a high mortality. About 95% of cases are
women and it has a population prevalence of about 1%, but evidence-based treatment is …

Reporting guidelines for human microbiome research: the STORMS checklist

C Mirzayi, A Renson… - Nature medicine, 2021 - nature.com
The particularly interdisciplinary nature of human microbiome research makes the
organization and reporting of results spanning epidemiology, biology, bioinformatics …

Microbiome-derived ethanol in nonalcoholic fatty liver disease

AS Meijnikman, M Davids, H Herrema, O Aydin… - Nature medicine, 2022 - nature.com
To test the hypothesis that the gut microbiota of individuals with nonalcoholic fatty liver
disease (NAFLD) produce enough ethanol to be a driving force in the development and …

A gut microbial signature for combination immune checkpoint blockade across cancer types

A Gunjur, Y Shao, T Rozday, O Klein, A Mu, BW Haak… - Nature medicine, 2024 - nature.com
Immune checkpoint blockade (ICB) targeting programmed cell death protein 1 (PD-1) and
cytotoxic T lymphocyte protein 4 (CTLA-4) can induce remarkable, yet unpredictable …

Health and disease markers correlate with gut microbiome composition across thousands of people

O Manor, CL Dai, SA Kornilov, B Smith… - Nature …, 2020 - nature.com
Variation in the human gut microbiome can reflect host lifestyle and behaviors and influence
disease biomarker levels in the blood. Understanding the relationships between gut …

Alterations of the gut microbiota in patients with coronavirus disease 2019 or H1N1 influenza

S Gu, Y Chen, Z Wu, Y Chen, H Gao… - Clinical Infectious …, 2020 - academic.oup.com
Abstract Background Coronavirus disease 2019 (COVID-19) is an emerging serious global
health problem. Gastrointestinal symptoms are common in COVID-19 patients, and severe …