Mammalian adipose tissue can be divided into two major types, namely, white adipose
tissue (WAT) and brown adipose tissue (BAT). According to classical view, the main function …

Beige or brite (brown-in-white) adipocytes are present in white adipose tissue (WAT) and
have a white fat-like phenotype that when stimulated acquires a brown fat-like phenotype …

While fatty acids (FAs) released by white adipose tissue (WAT) provide energy for other
organs, lipolysis is also critical in brown adipose tissue (BAT), generating FAs for oxidation …

The role of brown adipose tissue in the regulation of energy balance and maintenance of
body weight is well known in rodents. Recently, interest in this tissue has re-emerged due to …

Peroxisome proliferator activated receptor α (PPARα) is a distinctive marker of the brown fat
phenotype that has been proposed to coordinate the transcriptional activation of genes for …

Significance: Mitochondria are the energetic, metabolic, redox, and information signaling
centers of the cell. Substrate pressure, mitochondrial network dynamics, and cristae …

Evidence has accumulated that specific retinoids impact on developmental and biochemical
processes influencing mammalian adiposity including adipogenesis, lipogenesis, adaptive …

Insulin sensitivity deteriorates with age, but mechanisms remain unclear. Age‐related
changes in the function of subcutaneous white adipose tissue (sWAT) are less characterized …

Membrane uncoupling protein 3 (UCP3), a member of the mitochondrial uncoupling protein
family, was discovered in 1997. UCP3′ s properties, such as its high homology to other …

Obesity‐induced insulin resistance and type 2 diabetes mellitus can ultimately result in
various complications, including diabetic cardiomyopathy. In this case, cardiac dysfunction is …