The surface glycoconjugates of trypanosomatid parasites

MAJ Ferguson - … Transactions of the Royal Society of …, 1997 - royalsocietypublishing.org
Insect–transmitted protozoan parasites of the order Kinetoplastida, suborder
Trypanosomatina, include Trypanosoma brucei (aetiological agent of African slee** …

GPI-anchor synthesis in mammalian cells: genes, their products, and a deficiency

T Kinoshita, K Ohishi, J Takeda - The journal of biochemistry, 1997 - academic.oup.com
Protein GPI anchors are ubiquitous in eukaryotic cells. More than 50 mammalian proteins
are anchored to the membrane via GPI. GPI anchoring is a posttranslational modification …

[BOOK][B] Carbohydrates in chemistry and biology

B Ernst, GW Hart, P Sinaÿ - 2008 - pure.johnshopkins.edu
Abstract Carbohydrate Chemistry and Glycobiology have witnessed a rapid expansion
during the last few years with the development of numerous new, imaginative and efficient …

Inositol deacylation of glycosylphosphatidylinositol-anchored proteins is mediated by mammalian PGAP1 and yeast Bst1p

S Tanaka, Y Maeda, Y Tashima, T Kinoshita - Journal of Biological …, 2004 - ASBMB
The inositol moiety of mammalian glycosylphosphatidylinositol (GPI) is acylated at an early
step in GPI biosynthesis. The inositol acylation is essential for the generation of mature GPI …

Biosynthetic gene cluster of the glycopeptide antibiotic teicoplanin: characterization of two glycosyltransferases and the key acyltransferase

TL Li, F Huang, SF Haydock, T Mironenko… - Chemistry & biology, 2004 - cell.com
The gene cluster encoding biosynthesis of the clinically important glycopeptide antibiotic
teicoplanin has been cloned from Actinoplanes teichomyceticus. Forty-nine putative open …

Expression cloning of PIG-L, a CandidateN-Acetylglucosaminyl-phosphatidylinositol Deacetylase

N Nakamura, N Inoue, R Watanabe… - Journal of Biological …, 1997 - ASBMB
Many eukaryotic cell surface proteins are bound to the cell membrane by a
glycosylphosphatidylinositol (GPI) anchor. Several genes involved in GPI anchor …

Yeast ARV1 Is Required for Efficient Delivery of an Early GPI Intermediate to the First Mannosyltransferase during GPI Assembly and Controls Lipid Flow from the …

K Kajiwara, R Watanabe, H Pichler… - Molecular biology of …, 2008 - Am Soc Cell Biol
Glycosylphosphatidylinositol (GPI), covalently attached to many eukaryotic proteins, not only
acts as a membrane anchor but is also thought to be a sorting signal for GPI-anchored …

PIG-W is critical for inositol acylation but not for flip** of glycosylphosphatidylinositol-anchor

Y Murakami, U Siripanyapinyo, Y Hong… - Molecular biology of …, 2003 - Am Soc Cell Biol
Many cell surface proteins are anchored to a membrane via a glycosylphosphatidylinositol
(GPI), which is attached to the C termini in the endoplasmic reticulum. The inositol ring of …

[HTML][HTML] The GPI biosynthetic pathway as a therapeutic target for African slee** sickness

MAJ Ferguson, JS Brimacombe, JR Brown… - … et Biophysica Acta (BBA …, 1999 - Elsevier
African slee** sickness is a debilitating and often fatal disease caused by tsetse fly
transmitted African trypanosomes. These extracellular protozoan parasites survive in the …

Structural characterisation of two forms of procyclic acidic repetitive protein expressed by procyclic forms of Trypanosoma brucei

A Treumann, N Zitzmann, A Hülsmeier… - Journal of molecular …, 1997 - Elsevier
A procyclic acidic repetitive protein (PARP) fraction was purified from long-term cultures of
Trypanosoma brucei procyclic forms by a solvent-extraction and reverse phase …