lncRNA involvement in cancer stem cell function and epithelial-mesenchymal transitions
EM McCabe, TP Rasmussen - Seminars in cancer biology, 2021 - Elsevier
Epithelial to mesenchymal transition (EMT) is a cellular process in which cells composing
epithelial tissue lose requirements for physical contact with neighboring cells and acquire …
epithelial tissue lose requirements for physical contact with neighboring cells and acquire …
[HTML][HTML] Pharmacological basis and new insights of taxifolin: A comprehensive review
A Das, R Baidya, T Chakraborty, AK Samanta… - Biomedicine & …, 2021 - Elsevier
The pharmacological characteristics of phytochemicals have prompted a lot of interest in
their application in disease management. Due to the high incidence of cancer related …
their application in disease management. Due to the high incidence of cancer related …
[HTML][HTML] Integrated genomic and molecular characterization of cervical cancer
Cancer Genome Atlas Research Network - Nature, 2017 - ncbi.nlm.nih.gov
Cervical cancer remains one of the leading causes of cancer-related deaths worldwide.
Reported here is an extensive molecular characterization of 228 primary cervical cancers …
Reported here is an extensive molecular characterization of 228 primary cervical cancers …
The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer
AM Krebs, J Mitschke, M Lasierra Losada… - Nature cell …, 2017 - nature.com
Metastasis is the major cause of cancer-associated death. Partial activation of the epithelial-
to-mesenchymal transition program (partial EMT) was considered a major driver of tumour …
to-mesenchymal transition program (partial EMT) was considered a major driver of tumour …
The ZEB/miR‐200 feedback loop—a motor of cellular plasticity in development and cancer?
S Brabletz, T Brabletz - EMBO reports, 2010 - embopress.org
Epithelial‐to‐mesenchymal transition (EMT) is a fundamental process in development and
disease. Zinc‐finger enhancer binding (ZEB) transcription factors (ZEB1 and ZEB2) are …
disease. Zinc‐finger enhancer binding (ZEB) transcription factors (ZEB1 and ZEB2) are …
TGF-β-induced endothelial-mesenchymal transition in fibrotic diseases
E Pardali, G Sanchez-Duffhues… - International journal of …, 2017 - mdpi.com
Fibrotic diseases are characterized by net accumulation of extracellular matrix proteins in
affected organs leading to their dysfunction and ultimate failure. Myofibroblasts have been …
affected organs leading to their dysfunction and ultimate failure. Myofibroblasts have been …
To differentiate or not—routes towards metastasis
T Brabletz - Nature Reviews Cancer, 2012 - nature.com
Why are many metastases differentiated? Invading and disseminating carcinoma cells can
undergo an epithelial–mesenchymal transition (EMT), which is associated with a gain of …
undergo an epithelial–mesenchymal transition (EMT), which is associated with a gain of …
Cancer invasion: patterns and mechanisms
NV Krakhmal, MV Zavyalova, EV Denisov… - Acta Naturae …, 2015 - cyberleninka.ru
Cancer invasion and the ability of malignant tumor cells for directed migration and
metastasis have remained a focus of research for many years. Numerous studies have …
metastasis have remained a focus of research for many years. Numerous studies have …
Analysis of the role of the Hippo pathway in cancer
Y Han - Journal of translational medicine, 2019 - Springer
Cancer is a serious health issue in the world due to a large body of cancer-related human
deaths, and there is no current treatment available to efficiently treat the disease as the …
deaths, and there is no current treatment available to efficiently treat the disease as the …
[HTML][HTML] The role of miRNAs in colorectal cancer progression and chemoradiotherapy
Colorectal cancer (CRC) is known as the third most common cancer as well as the fourth
most deadly cancer worldwide. CRC accounts for approximately 10% of all new cancer …
most deadly cancer worldwide. CRC accounts for approximately 10% of all new cancer …