Tumor biomarkers for diagnosis, prognosis and targeted therapy

Y Zhou, L Tao, J Qiu, J Xu, X Yang, Y Zhang… - Signal transduction and …, 2024 - nature.com
Tumor biomarkers, the substances which are produced by tumors or the body's responses to
tumors during tumorigenesis and progression, have been demonstrated to possess critical …

Promising dawn in tumor microenvironment therapy: engineering oral bacteria

Z Wang, W Sun, R Hua, Y Wang, Y Li… - International Journal of …, 2024 - nature.com
Despite decades of research, cancer continues to be a major global health concern. The
human mouth appears to be a multiplicity of local environments communicating with other …

[HTML][HTML] Pharmacological basis and new insights of taxifolin: A comprehensive review

A Das, R Baidya, T Chakraborty, AK Samanta… - Biomedicine & …, 2021 - Elsevier
The pharmacological characteristics of phytochemicals have prompted a lot of interest in
their application in disease management. Due to the high incidence of cancer related …

lncRNA involvement in cancer stem cell function and epithelial-mesenchymal transitions

EM McCabe, TP Rasmussen - Seminars in cancer biology, 2021 - Elsevier
Epithelial to mesenchymal transition (EMT) is a cellular process in which cells composing
epithelial tissue lose requirements for physical contact with neighboring cells and acquire …

[HTML][HTML] Pericytes in the tumor microenvironment

Z Jiang, J Zhou, L Li, S Liao, J He, S Zhou, Y Zhou - Cancer letters, 2023 - Elsevier
Pericytes are a type of mural cell located between the endothelial cells of capillaries and the
basement membrane, which function to regulate the capillary vasomotor and maintain …

Integrated genomic and molecular characterization of cervical cancer

Cancer Genome Atlas Research Network - Nature, 2017 - pmc.ncbi.nlm.nih.gov
Cervical cancer remains one of the leading causes of cancer-related deaths worldwide.
Reported here is an extensive molecular characterization of 228 primary cervical cancers …

Analysis of the role of the Hippo pathway in cancer

Y Han - Journal of translational medicine, 2019 - Springer
Cancer is a serious health issue in the world due to a large body of cancer-related human
deaths, and there is no current treatment available to efficiently treat the disease as the …

[HTML][HTML] TGF-β-induced endothelial-mesenchymal transition in fibrotic diseases

E Pardali, G Sanchez-Duffhues… - International journal of …, 2017 - mdpi.com
Fibrotic diseases are characterized by net accumulation of extracellular matrix proteins in
affected organs leading to their dysfunction and ultimate failure. Myofibroblasts have been …

The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer

AM Krebs, J Mitschke, M Lasierra Losada… - Nature cell …, 2017 - nature.com
Metastasis is the major cause of cancer-associated death. Partial activation of the epithelial-
to-mesenchymal transition program (partial EMT) was considered a major driver of tumour …

An insight into novel therapeutic potentials of taxifolin

Y Liu, X Shi, Y Tian, S Zhai, Y Liu, Z **ong… - Frontiers in …, 2023 - frontiersin.org
Taxifolin is a flavonoid compound, originally isolated from the bark of Douglas fir trees,
which is often found in foods such as onions and olive oil, and is also used in commercial …