Adapting to obesity with adipose tissue inflammation
Adipose tissue not only has an important role in the storage of excess nutrients but also
senses nutrient status and regulates energy mobilization. An overall positive energy balance …
senses nutrient status and regulates energy mobilization. An overall positive energy balance …
Cell death and inflammation during obesity:“Know my methods, WAT (son)”
Obesity is a state of low-grade chronic inflammation that causes multiple metabolic
diseases. During obesity, signalling via cytokines of the TNF family mediate cell death and …
diseases. During obesity, signalling via cytokines of the TNF family mediate cell death and …
Properties and functions of adipose tissue macrophages in obesity
The expansion of adipose tissue (AT) in obesity is accompanied by the accumulation of
immune cells that contribute to a state of low‐grade, chronic inflammation and dysregulated …
immune cells that contribute to a state of low‐grade, chronic inflammation and dysregulated …
Adipose tissue remodeling: its role in energy metabolism and metabolic disorders
The adipose tissue is a central metabolic organ in the regulation of whole-body energy
homeostasis. The white adipose tissue functions as a key energy reservoir for other organs …
homeostasis. The white adipose tissue functions as a key energy reservoir for other organs …
[HTML][HTML] White adipose tissue dysfunction in obesity and aging
M Reyes-Farias, J Fos-Domenech, D Serra… - Biochemical …, 2021 - Elsevier
Both obesity and aging are associated with the development of metabolic diseases such as
type 2 diabetes and cardiovascular disease. Chronic low-grade inflammation of adipose …
type 2 diabetes and cardiovascular disease. Chronic low-grade inflammation of adipose …
Adipose tissue macrophages: going off track during obesity
L Boutens, R Stienstra - Diabetologia, 2016 - Springer
Inflammation originating from the adipose tissue is considered to be one of the main driving
forces for the development of insulin resistance and type 2 diabetes in obese individuals …
forces for the development of insulin resistance and type 2 diabetes in obese individuals …
Obesity and inflammation
J Karczewski, E Śledzińska, A Baturo, I Jończyk… - European cytokine …, 2018 - Springer
The prevalence of obesity has recently increased dramatically and has contributed to the
increasing prevalence of various pathological conditions, including type 2 diabetes mellitus …
increasing prevalence of various pathological conditions, including type 2 diabetes mellitus …
Mechanistic links between obesity, diabetes, and blood pressure: role of perivascular adipose tissue
SN Saxton, BJ Clark, SB Withers… - Physiological …, 2019 - journals.physiology.org
Obesity is increasingly prevalent and is associated with substantial cardiovascular risk.
Adipose tissue distribution and morphology play a key role in determining the degree of …
Adipose tissue distribution and morphology play a key role in determining the degree of …
Immunological complications of obesity
Current approaches for the treatment of obesity, including diet and lifestyle changes, have
not been successful in curtailing the obesity epidemic. The higher incidence of inflammation …
not been successful in curtailing the obesity epidemic. The higher incidence of inflammation …
Gut microbiota‐derived lipopolysaccharide uptake and trafficking to adipose tissue: implications for inflammation and obesity
LG Hersoug, P Møller, S Loft - Obesity Reviews, 2016 - Wiley Online Library
The composition of the gut microbiota and excessive ingestion of high‐fat diets (HFD) are
considered to be important factors for development of obesity. In this review we describe a …
considered to be important factors for development of obesity. In this review we describe a …