Inflammatory bowel diseases, which include Crohn's disease and ulcerative colitis, affect
several million individuals worldwide. Crohn's disease and ulcerative colitis are complex …

Cupriavidus necator is a bacterium with a high phenotypic diversity and versatile metabolic
capabilities. It has been extensively studied as a model hydrogen oxidizer, as well as a …

This paper presents a case study on the design, administration, post-processing, and
evaluation of surveys on large language models (LLMs). It comprises two components:(1) A …

The arrangement (syntax) of transcription factor (TF) binding motifs is an important part of the
cis-regulatory code, yet remains elusive. We introduce a deep learning model, BPNet, that …

Exploratory synthesis in new chemical spaces is the essence of solid-state chemistry.
However, uncharted chemical spaces can be difficult to navigate, especially when materials …

The reference human genome sequence set the stage for studies of genetic variation and its
association with human disease, but epigenomic studies lack a similar reference. To …

Neurophysiology has long progressed through exploratory experiments and chance
discoveries. Anecdotes abound of researchers listening to spikes in real time and noticing …

Summary Oct4, Sox2, Klf4, and cMyc (OSKM) reprogram somatic cells to pluripotency. To
gain a mechanistic understanding of their function, we mapped OSKM-binding, stage …

Skin homeostasis is orchestrated by dozens of cell types that together direct stem cell
renewal, lineage commitment, and differentiation. Here, we use single-cell RNA sequencing …

With the impressive growth of available data and the flexibility of network modelling, the
problem of devising effective quantitative methods for the comparison of networks arises …