Neurotrophic factors and neuroplasticity pathways in the pathophysiology and treatment of depression

MJF Levy, F Boulle, HW Steinbusch… - …, 2018 - Springer
Depression is a major health problem with a high prevalence and a heavy socioeconomic
burden in western societies. It is associated with atrophy and impaired functioning of cortico …

[HTML][HTML] Long-term potentiation and long-term depression: a clinical perspective

TVP Bliss, SF Cooke - Clinics, 2011 - Elsevier
Long-term potentiation and long-term depression are enduring changes in synaptic strength,
induced by specific patterns of synaptic activity, that have received much attention as cellular …

Visual experience induces long-term potentiation in the primary visual cortex

SF Cooke, MF Bear - Journal of Neuroscience, 2010 - Soc Neuroscience
Stimulus-specific response potentiation (SRP) is a robust form of experience-dependent
plasticity that occurs in primary visual cortex. In awake mice, visual evoked potentials (VEPs) …

Long-term plasticity of visually evoked potentials in humans is altered in major depression

C Normann, D Schmitz, A Fürmaier, C Döing… - Biological psychiatry, 2007 - Elsevier
BACKGROUND: Long-term synaptic plasticity is a ubiquitous form of neuronal plasticity that
regulates the strength of synaptic transmission in many brain areas. However, most data on …

TMS-induced cortical potentiation during wakefulness locally increases slow wave activity during sleep

R Huber, SK Esser, F Ferrarelli, M Massimini… - PloS one, 2007 - journals.plos.org
Background Sleep slow wave activity (SWA) is thought to reflect sleep need, increasing in
proportion to the length of prior wakefulness and decreasing during sleep. However, the …

The double edged sword of neural plasticity: increasing serotonin levels leads to both greater vulnerability to depression and improved capacity to recover

I Branchi - Psychoneuroendocrinology, 2011 - Elsevier
Major depression is a chronic, recurring and potentially life-threatening illness that affects up
to 10% of the population worldwide. Pharmacological and genetic studies highlight the …

Translating long-term potentiation from animals to humans: a novel method for noninvasive assessment of cortical plasticity

WC Clapp, JP Hamm, IJ Kirk, TJ Teyler - Biological psychiatry, 2012 - Elsevier
Long-term potentiation (LTP) is a synaptic mechanism underlying learning and memory that
has been studied extensively in laboratory animals. The study of LTP recently has been …

Impaired visual cortical plasticity in schizophrenia

I Çavuş, RMG Reinhart, BJ Roach, R Gueorguieva… - Biological …, 2012 - Elsevier
BACKGROUND: Impaired cortical plasticity may be part of the core pathophysiology of
schizophrenia (SZ). Long-term potentiation is a form of neuroplasticity that has been recently …

The role of Hebbian learning in human perception: a methodological and theoretical review of the human Visual Long-Term Potentiation paradigm

RL Sumner, MJ Spriggs… - Neuroscience & …, 2020 - Elsevier
Long-term potentiation (LTP) is one of the most widely studied forms of neural plasticity, and
is thought to be the principle mechanism underlying long-term memory and learning in the …

Learning without training

C Beste, HR Dinse - Current biology, 2013 - cell.com
Achieving high-level skills is generally considered to require intense training, which is
thought to optimally engage neuronal plasticity mechanisms. Recent work, however …