Clostridioides difficile infection: history, epidemiology, risk factors, prevention, clinical manifestations, treatment, and future options

S Di Bella, G Sanson, J Monticelli… - Clinical Microbiology …, 2024‏ - journals.asm.org
Clostridioides difficile infection (CDI) is one of the major issues in nosocomial infections.
This bacterium is constantly evolving and poses complex challenges for clinicians, often …

Clostridioides difficile: diagnosis and treatments

B Guery, T Galperine, F Barbut - Bmj, 2019‏ - bmj.com
Clostridioides difficile (formerly Clostridium) is a major cause of healthcare associated
diarrhea, and is increasingly present in the community. Historically, C difficile infection was …

Randomised clinical trial: faecal microbiota transplantation by colonoscopy vs. vancomycin for the treatment of recurrent Clostridium difficile infection

G Cammarota, L Masucci, G Ianiro… - Alimentary …, 2015‏ - Wiley Online Library
Background Faecal microbiota transplantation (FMT) from healthy donors is considered an
effective treatment against recurrent Clostridium difficile infection. Aim To study the effect of …

The use of fecal calprotectin testing in paediatric disorders: a position paper of the European Society for Paediatric Gastroenterology and Nutrition Gastroenterology …

CR Koninckx, E Donat, MA Benninga… - Journal of pediatric …, 2021‏ - journals.lww.com
Objectives: The aim of the study was to review the evidence regarding the clinical use and
value of fecal calprotectin (FC) measurements in different gastrointestinal disorders in …

Clostridium difficile

SR Curry - Clinics in laboratory medicine, 2010‏ - pmc.ncbi.nlm.nih.gov
Clostridium difficile infections (CDI) have emerged as one of the principal threats to the
health of hospitalized and immunocompromised patients. Nucleic acid testing for C. difficile …

Current knowledge on the laboratory diagnosis of Clostridium difficile infection

A Martínez-Meléndez, A Camacho-Ortiz… - World journal of …, 2017‏ - pmc.ncbi.nlm.nih.gov
Clostridium difficile (C. difficile) is a spore-forming, toxin-producing, gram-positive anaerobic
bacterium that is the principal etiologic agent of antibiotic-associated diarrhea. Infection with …

[PDF][PDF] Fecal Calprotectin Level Reflects the Severity of Clostridium difficile Infection.

J Kim, H Kim, HJ Oh, HS Kim… - Annals of laboratory …, 2017‏ - synapse.koreamed.org
Clostridium difficile is a significant nosocomial and community-acquired pathogen, and is
the leading cause of antibiotic-induced diarrhea associated with high morbidity and …

Diagnostic Guidance for C. difficile Infections

MJT Crobach, A Baktash, N Duszenko… - Updates on Clostridium …, 2018‏ - Springer
Diagnosis of Clostridium difficile infection (CDI) can be challenging. First of all, there has
been debate on which of the two reference assays, cell cytotoxicity neutralization assay …

Predictive value of fecal calprotectin and lactoferrin levels for negative outcomes in Clostridioides difficile infection

M Ágreda Fernández, J Origüen… - European Journal of …, 2024‏ - Springer
Purpose We investigated the role of fecal calprotectin (FC) and lactoferrin (FL) as predictive
biomarkers in Clostridioides difficile infection (CDI). Methods We assembled a prospective …

Faecal lactoferrin and calprotectin in patients with Clostridium difficile infection: a case–control study

F Barbut, C Gouot, N Lapidus, L Suzon… - European Journal of …, 2017‏ - Springer
Calprotectin and lactoferrin are released by the gastrointestinal tract in response to infection
and mucosal inflammation. Our objective was to assess the usefulness of quantifying faecal …