The ideal neuromuscular blocking agent (NMBA) is regarded as being a non-depolarizing
equivalent of succinylcholine, having a rapid onset and short duration of action, with minimal …

Starting from natural steroids (diosgenin, hecogenin, smilagenin, estrone), we have
prepared a wide panel of selenoderivatives, including benzoselenazolones …

Diosgenin, a component separated from Dioscorea plants, is an important starting material
for steroid hormone drugs and semisynthetic steroids. In the work, two series of diosgenin …

Giosgenin is a naturally steroidal saponin exhibiting a variety of biological activities
including antitumor ones. A series of novel diosgenyl quaternary ammonium derivatives …

RM-133 is a key representative of a new family of aminosteroids reported as potent
anticancer agents. Although RM-133 produced interesting results in 4 mouse xenograft …

Aconitine compounds are found in Aconitum Ouwu head, Chuan Wu, Aconitum, and other
Ranunculaceae aconitum plants, which are not only active ingredient but also toxic …

Neuromuscular blocking agents (NMBAs) are routinely used during anesthesia to relax
skeletal muscle. Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels; …

Neuromuscular blocking agents (NMBAs) are widely used in surgery to achieve skeleton
muscles relaxation under light anesthesia status. In this work, we synthesized a series of 3 …

The reactions of 21-hydroxyprogesterone with Lawesson's reagent in toluene or CH _ 2 Cl _
2 CH 2 Cl 2 gave four P-heterocyclic androst-4-ene derivatives (two tautomeric pairs): 4-(3 …

El presente trabajo contempla la síntesis y estudios computacionales de espiroimidazoles
esteroidales, los cuales contienen un grupo imidazol de tipo espiro sobre el C-17 de la …