This review summarizes current evidence on the abuse and misuse of the gabapentinoids
pregabalin and gabapentin. Pharmacovigilance studies, register-based studies, surveys …

The gabapentinoid drugs, gabapentin and pregabalin, are first-line treatments for
neuropathic pain. The epidemics of chronic pain and opioid misuse have given rise to the …

Introduction: Esketamine nasal spray received approval for treatment-resistant depression in
March 2019. Objective: Using the FDA Adverse Event Reporting System (FAERS) database …

Introduction: Gabapentinoid drugs (gabapentin and pregabalin) are widely used worldwide
for epileptic and pain disorders. First signals of gabapentinoid abuse occurred in the last …

In the past twenty years, the consumption of opioid medications has reached significant
proportions, leading to a rise in drug misuse and abuse and increased opioid dependence …

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BackgroundEvidence on neonatal withdrawal syndrome following antidepressant
intrauterine exposure is limited, particularly for antidepressants other than selective …

Background Prescription drug misuse in transgender individuals is estimated to be three
times higher than that of the general population in the United States, suggesting that opioid …

Purpose Gabapentin misuse is on the rise and has forced many US states to mobilize
policies to address this public health concern. The purpose of this manuscript is to update …

Objective The antinociceptive pharmacological interaction between N-
palmitoylethanolamide (PEA) and morphine (MOR), as well as gabapentin (GBP), was …