By providing spatial, molecular and morphological data over time, live-cell imaging can
provide a deeper understanding of the cellular and signalling events that determine cancer …

Central to the core principle of cell theory, depicting cells' history, state and fate is a
fundamental goal in modern biology. By leveraging clonal analysis and single-cell RNA-seq …

The optical microscope has revolutionized biology since at least the 17th Century. Since
then, it has progressed from a largely observational tool to a powerful bioanalytical platform …

The monitoring of tissue regeneration is particularly important. However, most materials do
not allow direct observation of the regeneration process in the cartilage layer. Here, using …

New drug modalities offer life-saving benefits for patients through access to previously
undruggable targets. Yet these modalities pose a challenge for the pharmaceutical industry …

From growing cells in spheroids to arranging them on complex engineered scaffolds, three-
dimensional cell culture protocols are rapidly expanding and diversifying. While these …

In this series of papers on light microscopy imaging, we have covered the fundamentals of
microscopy, super‐resolution microscopy, and lightsheet microscopy. This last review …

Endophytic fungi are used as the most common microbial biological control agents (MBCAs)
against phytopathogens and are ubiquitous in all plant parts. Most of the fungal species …

Signaling pathways play an important role in cell fate determination in stem cells and
regulate a plethora of developmental programs, the dysregulation of which can lead to …

Simple Summary In recent years, colorectal cancer stem cells (cCSCs) have been the object
of intense investigation for their promise to disclose new aspects of colorectal cancer cell …