Antibodies and antibody-derived macromolecules have established themselves as the
mainstay in protein-based therapeutic molecules (biologics). Our knowledge of the structure …

On the basis of comparative studies of known antibody structures and sequences it has
been argued that there is a small repertoire of main-chain conformations for at least five of …

This standard-setting textbook has defined the field of immunology since 1984, and is now in
its Seventh Edition continuing to deliver the detailed, authoritative, and timely coverage …

The structures of the various regions of an antibody molecule are analysed and correlated
with biological function. The structural features which relate to potential applications are …

A systematic exploration of the fascinating area of CH/p interaction-from the frontier of
chemical research The CH/p bond may be the weakest of the hydrogen bonds, but it has …

The structure of an intact, anti-canine lymphoma monoclonal antibody (Mab231) 1 was
determined by molecular replacement and refined in a triclinic cell to an R-value of 20.9 …

Publisher Summary The chapter discusses the protein stability with emphasis on compact
globular proteins representing a single cooperative system. All the small compact globular …

The 2.8 Å resolution three-dimensional structure of a complex between an antigen
(lysozyme) and the Fab fragment from a monoclonal antibody against lysozyme has been …

Biochemical Applications of Raman and Resonance Raman Spectroscopies focuses on the
application of Raman and resonance Raman spectroscopies to biochemical problems. The …

The topological connectivities of β-pleated sheets in the known protein structures are
systematically surveyed for regularly occurring features. The many empirical restrictions …