BACKGROUND: The American Heart Association (AHA), in conjunction with the National
Institutes of Health, annually reports the most up-to-date statistics related to heart disease …

Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …

Previous genome-wide association studies (GWASs) of stroke—the second leading cause of
death worldwide—were conducted predominantly in populations of European ancestry …

Cerebral small vessel disease (SVD) causes lacunar stroke and intracerebral hemorrhage,
and is the most common pathology underlying vascular cognitive impairment. Increasingly …

Perivascular space (PVS) burden is an emerging, poorly understood, magnetic resonance
imaging marker of cerebral small vessel disease, a leading cause of stroke and dementia …

Ischaemic stroke is a leading cause of disability and death for which no acute treatments
exist beyond recanalization. The development of novel therapies has been repeatedly …

Hypertension-associated cerebral small vessel disease is a common finding in older people.
Strongly associated with age and hypertension, small vessel disease is found at autopsy in …

Cerebral small vessel disease (cSVD) is a leading cause of ischaemic and haemorrhagic
stroke and a major contributor to dementia. Covert cSVD, which is detectable with brain MRI …

Ischemic stroke (IS) is one of the major types of cerebrovascular diseases causing
neurological morbidity and mortality worldwide. In the pathophysiological process of IS …

Background This study investigated the relationships of neutrophil count (NC), neutrophil-to-
lymphocyte ratio (NLR) and systemic immune-inflammation index (SII) with cerebral small …