Mechanisms of mitochondrial iron-sulfur protein biogenesis

R Lill, SA Freibert - Annual review of biochemistry, 2020 - annualreviews.org
Mitochondria are essential in most eukaryotes and are involved in numerous biological
functions including ATP production, cofactor biosyntheses, apoptosis, lipid synthesis, and …

[HTML][HTML] Mechanistic concepts of iron-sulfur protein biogenesis in Biology

JJ Braymer, SA Freibert, M Rakwalska-Bange… - Biochimica et Biophysica …, 2021 - Elsevier
Abstract Iron-sulfur (Fe/S) proteins are present in virtually all living organisms and are
involved in numerous cellular processes such as respiration, photosynthesis, metabolic …

[HTML][HTML] Regulation of iron homeostasis and use in chloroplasts

GE Kroh, M Pilon - International Journal of Molecular Sciences, 2020 - mdpi.com
Iron (Fe) is essential for life because of its role in protein cofactors. Photosynthesis, in
particular photosynthetic electron transport, has a very high demand for Fe cofactors. Fe is …

Function and biogenesis of iron–sulphur proteins

R Lill - Nature, 2009 - nature.com
Abstract Iron–sulphur (Fe–S) clusters have long been recognized as essential and versatile
cofactors of proteins involved in catalysis, electron transport and sensing of ambient …

[HTML][HTML] The role of mitochondria in cellular iron–sulfur protein biogenesis and iron metabolism

R Lill, B Hoffmann, S Molik, AJ Pierik… - … et Biophysica Acta (BBA …, 2012 - Elsevier
Mitochondria play a key role in iron metabolism in that they synthesize heme, assemble iron–
sulfur (Fe/S) proteins, and participate in cellular iron regulation. Here, we review the latter …

Iron utilization and metabolism in plants

JF Briat, C Curie, F Gaymard - Current opinion in plant biology, 2007 - Elsevier
The solubilization and long-distance allocation of iron between organs and tissues, as well
as its subcellular compartmentalization and remobilization, involve various chelation and …

Ancient and essential: the assembly of iron–sulfur clusters in plants

J Balk, M Pilon - Trends in plant science, 2011 - cell.com
In plants iron–sulfur (Fe–S) proteins are found in the plastids, mitochondria, cytosol and
nucleus, where they are essential for numerous physiological and developmental …

Fe-S cluster assembly pathways in bacteria

C Ayala-Castro, A Saini, FW Outten - Microbiology and Molecular …, 2008 - journals.asm.org
SUMMARY Iron-sulfur (Fe-S) clusters are required for critical biochemical pathways,
including respiration, photosynthesis, and nitrogen fixation. Assembly of these iron cofactors …

Iron–sulfur cluster biogenesis and human disease

TA Rouault, WH Tong - Trends in Genetics, 2008 - cell.com
Iron–sulfur (Fe–S) clusters are essential for numerous biological processes, including
mitochondrial respiratory chain activity and various other enzymatic and regulatory …

A fatal mitochondrial disease is associated with defective NFU1 function in the maturation of a subset of mitochondrial Fe-S proteins

A Navarro-Sastre, F Tort, O Stehling… - The American Journal of …, 2011 - cell.com
We report on ten individuals with a fatal infantile encephalopathy and/or pulmonary
hypertension, leading to death before the age of 15 months. Hyperglycinemia and lactic …