Topic Several patient-reported outcome measures (PROMs) are available to measure health-
related quality of life (HRQoL) in patients with late-stage clinical diabetic retinal diseases …

Background Current treatments for hemophilia A in Canada include on-demand treatment
as bleeds occur and regular intravenous prophylactic factor VIII (FVIII) infusions. The …

BACKGROUND Around 7500 people are diagnosed with non-muscle-invasive bladder
cancer in the UK annually. Recurrence following transurethral resection of bladder tumour is …

The rapid pace of discovery in genomics has been remarkable. The first human genome
was sequenced as recently as 2003, costing between US $500 million and US $1 billion [1] …

Background Bulbar urethral stricture is a common cause for urinary symptoms in men and its
two main treatment options both have drawbacks with little evidence on their relative cost …

Aim: To assess maintenance preference and trade-offs for patients with advanced epithelial
ovarian cancer. Methods: Patients completed a time trade-off exercise ranking five …

Background Recurrent urethral stricture is usually treated with either open urethroplasty or
endoscopic urethrotomy. Both of the procedures cause short-term utility loss, which may not …

Objectives To determine the effects of age, immigrant background, and poor self-reported
health in a general population sample on the probability of non-completion or slow …

Introduction Carer quality of life (QoL) can be included in economic evaluations and
captured using EQ-5D. Traditional valuation tasks require participants to imagine living in a …

Background: Hemophilia A is caused by a mutation of clotting factor genes resulting in a
deficiency of factor VIII (FVIII). Current treatments for hemophilia A in Canada include on …