Bile acids are soluble derivatives of cholesterol produced in the liver that subsequently
undergo bacterial transformation yielding a diverse array of metabolites. The bulk of bile …

Metabolomics aims at identification and quantitation of small molecules involved in
metabolic reactions. LC-MS has enjoyed a growing popularity as the platform for …

Early diagnosis has been proved to improve survival rate of lung cancer patients. The
availability of blood-based screening could increase early lung cancer patient uptake. Our …

Metabolomics research has recently gained popularity because it enables the study of
biological traits at the biochemical level and, as a result, can directly reveal what occurs in a …

Simple Summary Ovarian high-grade serous carcinoma (HGSC) has a 5-year survival rate
of less than 50%, making it one of the most lethal gynecological cancers for women in the …

Metabolomics allows the simultaneous and relative quantification of thousands of different
metabolites within a given sample using sensitive and specific methodologies such as gas …

Metabolomics is the comprehensive study of small molecule metabolites in biological
systems. By assaying and analyzing thousands of metabolites in biological samples, it …

The metabolome is the set of small molecular mass organic compounds found in a given
biological media. It includes all organic substances naturally occurring from the metabolism …

Introduction Untargeted metabolomics studies for biomarker discovery often have hundreds
to thousands of human samples. Data acquisition of large-scale samples has to be divided …

Mass spectrometry is an analytical technique for the characterization of biological samples
and is increasingly used in omics studies because of its targeted, nontargeted, and high …