The MR1/MAIT cell axis in CNS diseases
R Shrinivasan, SK Wyatt-Johnson… - Brain, behavior, and …, 2024 - Elsevier
Mucosal-associated invariant T (MAIT) cells are a subpopulation of innate-like T cells that
can be found throughout the body, predominantly in mucosal sites, the lungs and in the …
can be found throughout the body, predominantly in mucosal sites, the lungs and in the …
Bi-specific killer cell engager enhances NK cell activity against interleukin-13 receptor alpha-2 positive gliomas
KD Pawlowski, JT Duffy, A Tiwari, M Zannikou… - Cells, 2023 - mdpi.com
Glioblastoma (GBM) is a lethal brain tumor with limited therapeutic options. Bi-specific killer
cell engagers (BiKEs) are novel immunotherapies designed to engage natural killer (NK) …
cell engagers (BiKEs) are novel immunotherapies designed to engage natural killer (NK) …
Control of the temporal development of Alzheimer's disease pathology by the MR1/MAIT cell axis
Background Neuroinflammation is an important feature of Alzheimer's disease (AD).
Understanding which aspects of the immune system are important in AD may lead to new …
Understanding which aspects of the immune system are important in AD may lead to new …
Role of innate T cells in necrotizing enterocolitis
J Liu, S Joseph, K Manohar, J Lee, JP Brokaw… - Frontiers in …, 2024 - frontiersin.org
Necrotizing enterocolitis (NEC) is a destructive gastrointestinal disease primarily affecting
preterm babies. Despite advancements in neonatal care, NEC remains a significant cause of …
preterm babies. Despite advancements in neonatal care, NEC remains a significant cause of …
Multi-view spectral clustering with latent representation learning for applications on multi-omics cancer subty**
S Ge, J Liu, Y Cheng, X Meng… - Briefings in …, 2023 - academic.oup.com
Driven by multi-omics data, some multi-view clustering algorithms have been successfully
applied to cancer subtypes prediction, aiming to identify subtypes with biometric differences …
applied to cancer subtypes prediction, aiming to identify subtypes with biometric differences …
Mucosal-associated invariant T cells in cancer: dual roles, complex interactions and therapeutic potential
Mucosal-associated invariant T (MAIT) cells play diverse roles in cancer, infectious
diseases, and immunotherapy. This review explores their intricate involvement in cancer …
diseases, and immunotherapy. This review explores their intricate involvement in cancer …
Dysfunctional states of unconventional T-cell subsets in cancer
EN Katsnelson, A Spengler, J Domenico… - Journal of Leukocyte …, 2024 - academic.oup.com
Unconventional T cells represent a promising therapeutic agent to overcome the current
limitations of immunotherapies due to their universal T-cell receptors, ability to respond …
limitations of immunotherapies due to their universal T-cell receptors, ability to respond …
The Mechanism of Elizabethkingia miricola Infection of the Black Spotted Frog as Revealed by Multi-Omics Analysis
Q Wei, D Wang, K Wei, B Xu, J Xu - Fishes, 2024 - mdpi.com
Elizabethkingia miricola (E. miricola) is a significant pathogen that causes the crooked head
disease in black spotted frogs. This disease has plagued numerous frog farms in China and …
disease in black spotted frogs. This disease has plagued numerous frog farms in China and …
MAIT cells and MR1 play an immunosuppressive role in glioblastoma through the induction of neutrophils and MDSCs
T Hana, M Terabe - bioRxiv, 2022 - biorxiv.org
Background Major histocompatibility complex class I-related protein (MR1) is an antigen-
presenting molecule for Mucosal-Associated Invariant T (MAIT) cells. Although the …
presenting molecule for Mucosal-Associated Invariant T (MAIT) cells. Although the …
Elucidating the Characteristics and Functionality of the Mouse Mucosal-Associated Mucosal Invariant T (MAIT) Cell Receptor
R Shrinivasan - 2023 - scholarworks.iupui.edu
Mucosal-associated invariant T cells (MAIT) are a subset of invariant, innate-like T-cells that
are abundant in the gut lamina propria, kidney, lungs, and peripheral blood. MAIT cells are …
are abundant in the gut lamina propria, kidney, lungs, and peripheral blood. MAIT cells are …